ArticlePediatric nephrology (Berlin, Germany)2010
Very preterm birth is a risk factor for increased systolic blood pressure at a young adult age.
Article in Pediatric nephrology (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02147457 (Prematurity as Predictor of Children's Cardiovascular-renal Health), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH)
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- The Long-Term Effect of Preterm Birth on Renal Function: A Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Systematic review and meta-analysis of preterm birth and later systolic blood pressure.Hypertension (Dallas, Tex. : 1979) · 2012Pooled it
- The relationship between plasminogen activator inhibitor-1 levels and blood pressure in adolescents with a history of prematurity and/or low birth weight.Pediatric nephrology (Berlin, Germany) · 2026Article
- Associations of Nephron Number, Birth Weight, and Causes of Death in a Community at High Risk of Hypertension and Cardiovascular Disease.Kidney medicine · 2026Article
- Secondary Hypertension in Children-Identifying and Investigating at Risk Children.Current hypertension reports · 2025Review
- Prevalence and factors associated with hypertension among children attending pre-schools in Dar es Salaam, Tanzania.Italian journal of pediatrics · 2025Article
- Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis.Journal of family medicine and primary care · 2023Article
- Impaired renal clearance among Swedish adolescents born preterm.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- Baroreflex sensitivity and blood pressure in premature infants - dependence on gestational age, postnatal age and sex.Physiological research · 2021Article
- Postnatal Expression Profile of MicroRNAs Associated with Cardiovascular Diseases in 3- to 11-Year-Old Preterm-Born Children.Biomedicines · 2021Article
- Adrenal Steroid Metabolism and Blood Pressure in 5- to 7-Year-Old Children Born Preterm as Compared to Peers Born at Term.Frontiers in pediatrics · 2021Article
- Blood Pressure Variability and Baroreflex Sensitivity in Premature Newborns-An Effect of Postconceptional and Gestational Age.Frontiers in pediatrics · 2021Article
- Intrauterine growth restriction, preterm birth and risk of end-stage renal disease during the first 50 years of life.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
- Antenatal sildenafil citrate treatment increases offspring blood pressure in the placental-specificAmerican journal of physiology. Heart and circulatory physiology · 2020Article
- Article
- Paternal DNA Methylation May Be Associated With Gestational Age at Birth.Epigenetics insights · 2020Article
- Psychosocial developmental trajectory of a cohort of young adults born very preterm and/or with a very low birth weight in the Netherlands.Journal of patient-reported outcomes · 2019Article
- Prenatal lead exposure modifies the effect of shorter gestation on increased blood pressure in children.Environment international · 2018Article
- Long-term effects of premature birth on somatic development in women through adolescence and adulthood.The Journal of international medical research · 2018Article
- The path to chronic kidney disease following acute kidney injury: a neonatal perspective.Pediatric nephrology (Berlin, Germany) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Children born very prematurely who show intrauterine growth retardation (IUGR) are suggested to be at risk of developing high blood pressure as adults. Renal function may already be impaired by young adult age. To study whether very preterm birth affects blood pressure in young adults, we measured 24-h ambulatory blood pressure (Spacelabs 90207 device) and renin concentration in 50 very premature individuals (<32 weeks of gestation), either small (SGA) or appropriate (AGA) for gestational age (21 SGA, 29 AGA), and 30 full-term controls who all were aged 20 years at time of measurement. The mean (standard deviation) daytime systolic blood pressure in SGA and AGA prematurely born individuals, respectively, was 122.7 (8.7) and 123.1 (8.5) mmHg. These values were, respectively, 3.6 mmHg [95% confidence interval (CI) -0.9 to 8.0] and 4.2 mmHg (95% CI 0.4-8.0) higher than in controls [119.6 (7.6)]. Daytime diastolic blood pressure and nighttime blood pressure did not differ between groups. We conclude that individuals born very preterm have higher daytime systolic blood pressure and higher risk of hypertension at a young adult age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.