ReviewMammalian genome : official journal of the International Mammalian Genome Society2010
Computational approaches for microRNA studies: a review.
Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
70 citing papers in PubMed.
- A comprehensive review on RNA subcellular localization prediction.Briefings in functional genomics · 2026Review
- Exploration of microRNAs as transcriptional regulator in mumps virus infection through computational studies.Scientific reports · 2024Article
- The Application of MicroRNAs in Glaucoma Research: A Bibliometric and Visualized Analysis.International journal of molecular sciences · 2023Article
- Role of phasiRNAs in plant-pathogen interactions: molecular perspectives and bioinformatics tools.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Review
- MicroRNA let-7 and viral infections: focus on mechanisms of action.Cellular & molecular biology letters · 2022Review
- Identification of Long Non-coding RNA Transcripts inIranian journal of biotechnology · 2022Article
- Article
- Deep Learning for the discovery of new pre-miRNAs: Helping the fight against COVID-19.Machine learning with applications · 2021Article
- Let-7a-5p, miR-100-5p, miR-101-3p, and miR-199a-3p Hyperexpression as Potential Predictive Biomarkers in Early Breast Cancer Patients.Journal of personalized medicine · 2021Article
- MicroRNA and Hemophilia-A Disease: Bioinformatics Prediction and Experimental Analysis.Cell journal · 2021Article
- Novel approaches on identification of conserved miRNAs for broad-spectrum Potyvirus control measures.Molecular biology reports · 2021Article
- The Role of Deregulated MicroRNAs in Age-Related Macular Degeneration Pathology.Translational vision science & technology · 2021Article
- MicroRNA bta-miR-365-3p inhibits proliferation but promotes differentiation of primary bovine myoblasts by targeting the activin A receptor type I.Journal of animal science and biotechnology · 2021Article
- Hybrid Deep Neural Network for Handling Data Imbalance in Precursor MicroRNA.Frontiers in public health · 2021Article
- Characterizing the tumor RBP-ncRNA circuits by integrating transcriptomics, interactomics and clinical data.Computational and structural biotechnology journal · 2021Article
- MicroRNAs signatures, bioinformatics analysis of miRNAs, miRNA mimics and antagonists, and miRNA therapeutics in osteosarcoma.Cancer cell international · 2020Review
- Computational prediction and characterisation of miRNAs and their pathway genes in human schistosomiasis caused by Schistosoma haematobium.Memorias do Instituto Oswaldo Cruz · 2020Article
- Improved Pre-miRNAs Identification Through Mutual Information of Pre-miRNA Sequences and Structures.Frontiers in genetics · 2019Article
- New insights into tomato microRNAs.Scientific reports · 2018Article
- Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are one class of tiny, endogenous RNAs that can regulate messenger RNA (mRNA) expression by targeting homologous sequences in mRNAs. Their aberrant expressions have been observed in many cancers and several miRNAs have been convincingly shown to play important roles in carcinogenesis. Since the discovery of this small regulator, computational methods have been indispensable tools in miRNA gene finding and functional studies. In this review we first briefly outline the biological findings of miRNA genes, such as genomic feature, biogenesis, gene structure, and functional mechanism. We then discuss in detail the three main aspects of miRNA computational studies: miRNA gene finding, miRNA target prediction, and regulation of miRNA genes. Finally, we provide perspectives on some emerging issues, including combinatorial regulation by miRNAs and functional binding sites beyond the 3'-untranslated region (3'UTR) of target mRNAs. Available online resources for miRNA computational studies are also provided.
Indexed as
Identifiers
20012966What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.