ArticleImmunogenetics2010
Developmental and tissue-specific expression of NITRs.
Article in Immunogenetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma.eLife · 2025Article
- Direct male development in chromosomally ZZ zebrafish.Frontiers in cell and developmental biology · 2024Article
- Multi-tissue scRNA-seq reveals immune cell landscape of turbot (Fundamental research · 2022Article
- Holosteans contextualize the role of the teleost genome duplication in promoting the rise of evolutionary novelties in the ray-finned fish innate immune system.Immunogenetics · 2021Article
- Resident Immunity in Tissue Repair and Maintenance: The Zebrafish Model Coming of Age.Frontiers in cell and developmental biology · 2019Article
- Single-cell transcriptional analysis reveals ILC-like cells in zebrafish.Science immunology · 2018Article
- How Surrogate and Chemical Genetics in Model Organisms Can Suggest Therapies for Human Genetic Diseases.Genetics · 2018Review
- Spotted Gar and the Evolution of Innate Immune Receptors.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2017Article
- The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes.Immunogenetics · 2016Article
- The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.Infection and immunity · 2015Article
- Neutralization of mitochondrial superoxide by superoxide dismutase 2 promotes bacterial clearance and regulates phagocyte numbers in zebrafish.Infection and immunity · 2015Article
- Animal models of tuberculosis: zebrafish.Cold Spring Harbor perspectives in medicine · 2014Review
- Multigene families of immunoglobulin domain-containing innate immune receptors in zebrafish: deciphering the differences.Developmental and comparative immunology · 2014Review
- Differential expression and ligand binding indicate alternative functions for zebrafish polymeric immunoglobulin receptor (pIgR) and a family of pIgR-like (PIGRL) proteins.Immunogenetics · 2014Article
- Article
- Development and characterization of anti-nitr9 antibodies.Advances in hematology · 2012Article
- A model 450 million years in the making: zebrafish and vertebrate immunity.Disease models & mechanisms · 2012Review
- Structural and functional diversity of the lectin repertoire in teleost fish: relevance to innate and adaptive immunity.Developmental and comparative immunology · 2011Review
- Host-pathogen interactions made transparent with the zebrafish model.Current drug targets · 2011Review
- The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities.Immunogenetics · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Novel immune-type receptors (NITRs) are encoded by large multi-gene families and share structural and signaling similarities to mammalian natural killer receptors (NKRs). NITRs have been identified in multiple bony fish species, including zebrafish, and may be restricted to this large taxonomic group. Thirty-nine NITR genes that can be classified into 14 families are encoded on zebrafish chromosomes 7 and 14. Herein, we demonstrate the expression of multiple NITR genes in the zebrafish ovary and during embryogenesis. All 14 families of zebrafish NITRs are expressed in hematopoietic kidney, spleen and intestine as are immunoglobulin and T cell antigen receptors. Furthermore, all 14 families of NITRs are shown to be expressed in the lymphocyte lineage, but not in the myeloid lineage, consistent with the hypothesis that NITRs function as NKRs. Sequence analyses of NITR amplicons identify known alleles and reveal additional alleles within the nitr1, nitr2, nitr3, and nitr5 families, reflecting the recent evolution of this gene family.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.