ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2010
Diagnostic and clinical benefit of combined coronary calcium and perfusion assessment in patients undergoing PET/CT myocardial perfusion stress imaging.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 64 citations in OpenAlex.
- Combined evaluation of CAC score and myocardial perfusion imaging in patients at risk of cardiovascular disease: where are we and what do the data say.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Hybrid nuclear/CT cardiac imaging: Pros cons and the future.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Combining myocardial perfusion imaging with coronary artery calcium scoring: The time is NOW!Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Myocardial perfusion imaging for diabetes: Key points from the evidence and clinical questions to be answered.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease.European journal of nuclear medicine and molecular imaging · 2020Article
- Automated calcium scores collected during myocardial perfusion imaging improve identification of obstructive coronary artery disease.International journal of cardiology. Heart & vasculature · 2020Article
- CT attenuation correction for thallium SPECT MPI and other benefits of multimodality imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Coronary calcium score influences referral for invasive coronary angiography after normal myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Use of coronary artery calcium scanning as a triage for invasive coronary angiography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Diagnostic accuracy ofCardiovascular diagnosis and therapy · 2019Article
- Coronary Calcium Score and Cardiovascular Risk.Journal of the American College of Cardiology · 2018Review
- Combined evaluation of regional coronary artery calcium and myocardial perfusion byEuropean journal of nuclear medicine and molecular imaging · 2018Article
- Prognostic value of atherosclerotic burden and coronary vascular function in patients with suspected coronary artery disease.European journal of nuclear medicine and molecular imaging · 2017Article
- Detection of non-obstructive coronary artery disease: Is post-stress diastolic dysfunction assessed by myocardial perfusion imaging a useful tool?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Mitochondrial-Targeted Molecular Imaging in Cardiac Disease.BioMed research international · 2017Review
- Value-based imaging: Combining coronary artery calcium with myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Review
- Review
- Combining stress-only myocardial perfusion imaging with coronary calcium scanning as a new paradigm for initial patient work-up: an exploratory analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Increased intrathoracic and hepatic visceral adipose tissue independently correlates with coronary artery calcification in asymptomatic patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA limitation of stress myocardial perfusion imaging (MPI) is the inability to detect non-obstructive coronary artery disease (CAD). One advantage of MPI with a hybrid CT device is the ability to obtain same-setting measurement of the coronary artery calcium score (CACS). METHODS AND
resultsUtilizing our single-center nuclear database, we identified 760 consecutive patients with: (1) no CAD history; (2) a normal clinically indicated Rb-82 PET/CT stress perfusion study; and (3) a same-setting CAC scan. 487 of 760 patients (64.1%) had subclinical CAD based on an abnormal CACS. Of those with CAC, the CACS was > or =100, > or =400, and > or =1000 in 47.0%, 22.4%, and 8.4% of patients, respectively. Less than half of the patients with CAC were receiving aspirin or statin medications prior to PET/CT imaging. Patients with CAC were more likely to be initiated or optimized on proven medical therapy for CAD immediately following PET/CT MPI compared to those without CAC.
conclusionsSubclinical CAD is common in patients without known CAD and normal myocardial perfusion assessed by hybrid PET/CT imaging. Identification of CAC influences subsequent physician prescribing patterns such that those with CAC are more likely to be treated with proven medical therapy for the treatment of CAD.
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