Evidence map›Paper›PMID 20012448›Full record

Trial reportEuropean journal of applied physiology2010

Increase in calf post-occlusive blood flow and strength following short-term resistance exercise training with blood flow restriction in young women.

Stephen D Patterson, Richard A Ferguson

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04248413 (Blood Flow Restriction Training Following Acute Shoulder Injury In Baseball Players), which is not on this map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04248413 nawithdrawnnot on this mapstarted 2022, after this paper: background citation

Blood Flow Restriction Training Following Acute Shoulder Injury In Baseball Players: Assessment of Efficacy in Return to Sport

TypeinterventionalSponsorWake Forest University Health SciencesRan2022 to 2022Enrolled0ConditionsMusculoskeletal InjuryArmsBlood Flow Restriction Therapy, Standard physical rehabilitation
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 136 citations in OpenAlex.

  1. Pooled it
  2. Low intensity blood flow restriction training: a meta-analysis.European journal of applied physiology · 2012
    Pooled it
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  8. Post-exercise blood flow restriction attenuates muscle hypertrophy.European journal of applied physiology · 2016
    Trial
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  15. Article
  16. Review
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  19. Hemodynamic analysis of blood flow restriction training: a systematic review.BMC sports science, medicine & rehabilitation · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephen D PattersonSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, Leicestershire, LE11 3TU, UK.
Richard A Ferguson
Loughborough University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The response of calf muscle strength, resting (R (bf)) and post-occlusive (PO(bf)) blood flow were investigated following 4 weeks resistance training with and without blood flow restriction in a matched leg design. Sixteen untrained females performed unilateral plantar-flexion low-load resistance training (LLRT) at either 25% (n = 8) or 50% (n = 8) one-repetition maximum (1 RM). One limb was trained with unrestricted blood flow whilst in the other limb blood flow was restricted with the use of a pressure applied cuff above the knee (110 mmHg). Regardless of the training load, peak PO(bf), measured using venous occlusion plethysmography increased when LLRT was performed with blood flow restriction compared to no change following LLRT with unrestricted blood flow. A significant increase (P < 0.05) in the area under the blood time-flow curve was also observed following LLRT with blood flow restriction when compared LLRT with unrestricted blood flow. No changes were observed in R (bf) between groups following training. Maximal dynamic strength (1 RM), maximal voluntary contraction and isokinetic strength at 0.52 and 1.05 rad s(-1) also increased (P < 0.05) by a greater extent following resistance training with blood flow restriction. Moreover, 1 RM increased to a greater extent following training at 50% 1 RM compared to 25% 1 RM. These results suggest that 4 weeks LLRT with blood flow restriction provides a greater stimulus to increase peak PO(bf) as well as strength parameters than LLRT with unrestricted blood flow.

Indexed as

Resistance TrainingAdaptation, PhysiologicalAdultExerciseFemaleHumansLegMuscle, SkeletalMuscle StrengthRegional Blood FlowReperfusionTime FactorsUp-RegulationVenous InsufficiencyYoung Adult

Identifiers

PMID20012448
OpenAlexW2037426331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.