Evidence map›Paper›PMID 20012182›Full record

ArticleCancer causes & control : CCC2010

Determinants of serum 25 hydroxyvitamin D levels in a nationwide cohort of blacks and non-Hispanic whites.

Jacqueline Chan, Karen Jaceldo-Siegl, Gary E Fraser

Open access · greenAbstract read
In one paragraph

Article in Cancer causes & control : CCC, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  9. Vitamin D: And its role in breast cancer.The Kaohsiung journal of medical sciences · 2018
    Review
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  17. Review
  18. VITAMIN D-BINDING PROTEIN IN HEALTHY PRE- AND POSTMENOPAUSAL WOMEN: RELATIONSHIP WITH ESTRADIOL CONCENTRATIONS.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jacqueline ChanDepartment of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, 24785 Stewart St, Loma Linda, CA 92350, USA.
Karen Jaceldo-Siegl
Gary E Fraser
Loma Linda University · US

Funding

CANCER EPIDEMIOLOGY IN ADVENTISTS--A LOW RISK GROUPR01CA094594 · NCI · LOMA LINDA UNIVERSITY · PI FRASER, GARY E. · 2001 to 2008
$18.0M
Plant-based diets and risk of cancerU01CA152939 · NCI · LOMA LINDA UNIVERSITY · PI FRASER, GARY E. · 2011 to 2015
$5.7M
Impact of Vitamin D on Heart Disease and Total MortalityF32HL082435 · NHLBI · LOMA LINDA UNIVERSITY · PI CHAN, JACQUELINE · 2005 to 2008
$174k
NCI NIH HHS R01 CA094594NCI NIH HHS R01 CA94594NCI NIH HHS U01 CA152939NHLBI NIH HHS 5F32HL082435NHLBI NIH HHS F32 HL082435
6 · The paper itself

Abstract

objectiveTo develop algorithms predicting serum 25 hydroxyvitamin D [s25(OH)D] for a large epidemiological study whose subjects come from large geographic areas, are racially diverse and have a wide range in age, skin types, and month of blood sample collection. This will allow a regression calibration approach to determine s25(OH)D levels replacing the more costly method of collection and analysis of blood samples. STUDY DESIGN AND

settingQuestionnaire data from a subsample of 236 non-Hispanic whites (whites) and 209 blacks from the widely dispersed Adventist Health Study-2 (n = 96,000) were used to develop prediction algorithms for races separately and combined. A single blood sample was collected from each subject, at different times throughout the year.

resultsModels with independent variables age, sex, BMI, skin type, UV season, erythemal zone, total dietary vitamin D intake, and sun exposure factor explained 22 and 31% of the variance of s25(OH)D levels in white and black populations, respectively (42% when combined). UV season and erythemal zone determined from measured UV radiation produced models with higher R (2) than season and latitude.

conclusionCombining races with a term for race and using variables with measured UV radiation capture the variance in s25(OH)D levels better than analyzing races separately.

Indexed as

AdultAgedAged, 80 and overAlcohol DrinkingBlack or African AmericanBlack PeopleCanadaCohort StudiesDietary SupplementsErythemaFemaleHumansMaleMultivariate AnalysisRegression AnalysisRisk Factors25-hydroxyvitamin DVitamin D

Identifiers

PMID20012182
PMCPMC3427006
OpenAlexW2088784475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.