ReviewCanadian journal of gastroenterology = Journal canadien de gastroenterologie2009
The role of iron in the pathophysiology and treatment of chronic hepatitis C.
Review in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 65 citations in OpenAlex.
- Hepatic iron accumulation is reduced in the cholestatic Mdr2-/- mouse.Bioscience reports · 2026Article
- Coordination of AMPK and YAP byInternational journal of molecular sciences · 2022Article
- Transforming a clinical fluorescent dye to sense and treat iron overload disorders: a new reverse translational approach in precision medicine.Quantitative imaging in medicine and surgery · 2022Article
- MicroRNA profile and iron-related gene expression in hepatitis C-related hepatocellular carcinoma: a preliminary study.Archives of medical science : AMS · 2021Article
- Co-infections as Modulators of Disease Outcome: Minor Players or Major Players?Frontiers in microbiology · 2021Review
- Article
- Determination of mutations in iron regulating genes of beta thalassemia major patients of Khyber Pakhtunkhwa, Pakistan.Molecular genetics & genomic medicine · 2020Article
- Liver clear cell foci and viral infection are associated with non-cirrhotic, non-fibrolamellar hepatocellular carcinoma in young patients from South America.Scientific reports · 2018Article
- Serum Markers of Iron Metabolism in Chronic Liver Diseases.Open access Macedonian journal of medical sciences · 2018Article
- Interferon lambda polymorphisms associate with body iron indices and hepatic expression of interferon-responsive long non-coding RNA in chronic hepatitis C.Clinical and experimental medicine · 2017Article
- Relationship between Hepatitis C Virus Infection and Iron Overload.Chinese medical journal · 2017Review
- Diffusion-weighted imaging of the liver: Current applications.World journal of radiology · 2016Review
- Iron Overload in Patients With Chronic Liver Disease.Gastroenterology & hepatology · 2016Article
- Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virus-infected liver.World journal of gastroenterology · 2015Article
- Supplementation of Citrus maxima Peel Powder Prevented Oxidative Stress, Fibrosis, and Hepatic Damage in Carbon Tetrachloride (CCl4) Treated Rats.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Mechanistic and regulatory aspects of intestinal iron absorption.American journal of physiology. Gastrointestinal and liver physiology · 2014Review
- Article
- Serum iron markers in patients with chronic hepatitis C infection.Hepatitis monthly · 2013Article
- Prevention of hepatocellular carcinoma: potential targets, experimental models, and clinical challenges.Current cancer drug targets · 2012Review
- Hepatitis C, porphyria cutanea tarda and liver iron: an update.Liver international : official journal of the International Association for the Study of the Liver · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Increased hepatic iron content may be observed in patients with chronic hepatitis C infection, and may contribute to disease severity. The presence of hemochromatosis gene mutations is associated with increased hepatic iron accumulation and may lead to accelerated disease progression. Hepatic iron depletion has been postulated to decrease the risk of hepatocellular carcinoma in patients with cirrhosis due to chronic hepatitis C. It is possible that iron depletion stabilizes or improves liver histology and slows disease progression in these individuals. The present article reviews the prevalence and risk factors for hepatic iron overload in chronic hepatitis C, with emphasis on the available data regarding the efficacy of iron depletion in the treatment of this common liver disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.