ArticleClinics in colon and rectal surgery2008
Extracolonic manifestations of hereditary colorectal cancer syndromes.
Article in Clinics in colon and rectal surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04168931 (Efficacy of Adding Trastuzumab to Standard Chemotherapy in Patients With Advanced HER2-negative Gastric Cancer and HER2 Positive Expression in Circulating Tumor Cells), which is not on this map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Adding Trastuzumab to Standard Chemotherapy in Patients With Advanced HER2-negative Gastric Cancer and HER2 Positive Expression in Circulating Tumor Cells
Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- High Grade Dysplastic Rectal Adenoma in a Young Patient With Café-Au-Lait Spots: A Case Report.Clinical case reports · 2025Article
- Genome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening.British journal of cancer · 2024Article
- How many is too many? Polyposis syndromes and what to do next.Current opinion in gastroenterology · 2022Review
- Cribiform-morular variant of papillary thyroid carcinoma and familial adenomatous polyposis: Report of a case.Acta bio-medica : Atenei Parmensis · 2021Article
- Colorectal Cancer and Probiotics: Are Bugs Really Drugs?Cancers · 2020Review
- Thymic cancer in lynch syndrome: an unusual association.BMJ case reports · 2020Article
- Hereditary Polyposis Syndromes.Current treatment options in gastroenterology · 2019Review
- APC mosaicism in a young woman with desmoid type fibromatosis and familial adenomatous polyposis.Familial cancer · 2018Article
- Desmoid tumors: clinical features and outcome of an unpredictable and challenging manifestation of familial adenomatous polyposis.Familial cancer · 2015Article
- Familial Adenomatous Polyposis (FAP)-A Case Study and Review of Literature.Journal of clinical and diagnostic research : JCDR · 2015Article
- Chemoprevention of colorectal cancer.Digestive diseases (Basel, Switzerland) · 2015Review
- Familial adenomatous polyposis in three generations of a single family: a case study.Case reports in oncology · 2014Article
- Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: report of a case.World journal of surgical oncology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Familial colorectal adenocarcinoma (CRC) accounts for approximately 15 to 20% of CRC. Of these, hereditary nonpolyposis colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP) represent the most common hereditary syndromes associated with CRC, followed by other less common diseases including juvenile polyposis (JP) and Peutz-Jeghers syndrome (PJS). Extracolonic manifestations are common in each of these syndromes having significant implications for surveillance and management in at-risk individuals. The authors review the most common and clinically relevant extracolonic manifestations for each of these syndromes focusing on incidence, presentation, genotype/phenotype correlations, and management (including surveillance) strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.