ReviewCanadian journal of surgery. Journal canadien de chirurgie2009
Factors influencing antibiotic prophylaxis for surgical site infection prevention in general surgery: a review of the literature.
Review in Canadian journal of surgery. Journal canadien de chirurgie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk predictions of surgical wound complications based on a machine learning algorithm: A systematic review.International wound journal · 2024Pooled it
- Pooled it
- Facilitation as an effective strategy to reduce excessive antibiotic prophylaxis in Children's hospitals: A stepped-wedge cluster randomized controlled trial.Implementation science : IS · 2025Trial
- Trial
- Surgical Site Infection Prevention Research: A Bibliometric Analysis of the Top 50 Highly Cited Articles.Cureus · 2026Review
- Antibacterial evaluation of antibiotic-coated titanium and stainless steel implants in orthopaedic application: a dip-coating approach.Journal of orthopaedic surgery and research · 2025Article
- Article
- Controversies and Future Directions in Management of Acute Appendicitis: An Updated Comprehensive Review.Journal of clinical medicine · 2024Review
- Posterior cranial vault distraction in children with syndromic craniosynostosis: the era of biodegradable materials-a comprehensive review of the literature and proposed novel global application.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- Antibiotic Prophylaxis in Surgery: Current Insights and Future Directions for Surgical Site Infection Prevention.Cureus · 2023Review
- Open tibial shaft fractures: treatment patterns in sub-Saharan Africa.OTA international : the open access journal of orthopaedic trauma · 2023Article
- Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery.Antibiotics (Basel, Switzerland) · 2023Review
- Article
- Incidence, risk factors and outcomes of surgical site infections among patients admitted to Jimma Medical Center, South West Ethiopia: Prospective cohort study.Annals of medicine and surgery (2012) · 2021Article
- Assessment of Antibiotic Prophylaxis in Surgical Patients and Association Factors at Thu Duc District Hospital, Ho Chi Minh City, Vietnam in 2018.Health services insights · 2021Article
- Perioperative Antibiotic Prophylaxis: Knowledge and Attitudes among Resident Physicians in Italy.Antibiotics (Basel, Switzerland) · 2020Article
- A retrospective analysis of factors affecting surgical site infection in orthopaedic patients.The Journal of international medical research · 2020Article
- Evaluation of Surgical Antimicrobial Prophylaxis and Incidence of Surgical Site Infection at Borumeda Hospital, Northeast Ethiopia: Retrospective Cross-Sectional Study.Drug, healthcare and patient safety · 2020Article
- Article
- Predictors of surgical site infection after radical cystectomy: should we enhance surgical antibiotic prophylaxis?World journal of urology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical site infections (SSIs) are common surgical complications that can be prevented with antibiotic prophylaxis. Research shows poor adherence to guidelines for this practice. We conducted a scoping review to identify factors or interventions that influence antibiotic prophylaxis administration.
methodsAn investigator with informatics training searched indexed (MEDLINE, Cochrane Library) and nonindexed (Internet) sources from January 1996 to February 2007. Selected studies were English-language, peer-reviewed, quantitative or qualitative studies describing factors or interventions influencing adherence to SSI-prevention guidelines or SSI rates in general surgery. Two investigators independently reviewed citations and full-text articles and extracted data, and met to compare selections or data and resolve differences through discussion. We extracted data on type of surgery, study design, intervention or factors examined and key findings. We then examined the quantity and type of studies and their findings.
resultsNineteen of 192 studies met the eligibility criteria. Seven studies investigated predictors of appropriate antibiotic use through descriptive or exploratory means. Twelve evaluated adherence to antibiotic prophylaxis recommendations by comparing patient cohorts before and after the introduction of quality-improvement strategies. Individual knowledge, attitudes, beliefs and practice; team communication and allocation of responsibilities; and institutional support for promoting and monitoring practice appear to influence practice.
conclusionLarger and multisite studies included in our review favour implementation of multidisciplinary pathways, individualized performance data and written or computerized order sets as quality-improvement strategies, but further research is warranted to more rigorously evaluate the effectiveness of these strategies on antibiotic prophylaxis practice.
Indexed as
Identifiers
20011184PMC2792388What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.