ArticleCanadian journal of surgery. Journal canadien de chirurgie2009
Outcomes of simultaneous and delayed resections of synchronous colorectal liver metastases.
Article in Canadian journal of surgery. Journal canadien de chirurgie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Simultaneous versus staged colorectal and hepatic resections for colorectal cancer with synchronous hepatic metastases: a meta-analysis of outcomes and clinical characteristics.International journal of colorectal disease · 2020Pooled it
- Pooled it
- Chinese guidelines for the diagnosis and comprehensive treatment of hepatic metastasis of colorectal cancer.Journal of cancer research and clinical oncology · 2011Guideline
- Simultaneous vs. staged resection for synchronous colorectal liver metastases: a metaanalysis.International journal of colorectal disease · 2011Pooled it
- Perioperative Outcomes Following Combined Versus Isolated Colorectal and Liver Resections:Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2021Article
- Simultaneous, Delayed and Liver-First Hepatic Resections for Synchronous Colorectal Liver Metastases: A Systematic Review and Network Meta-Analysis.Journal of clinical medicine research · 2019Article
- Prognostic analysis and liver metastases relevant factors after gastric and hepatic surgical treatment in gastric cancer patients with metachronous liver metastases: a population-based study.Irish journal of medical science · 2019Article
- Management of colorectal cancer presenting with synchronous liver metastases.Nature reviews. Clinical oncology · 2014Review
- Strategies for Management of Synchronous Colorectal Metastases.Current surgery reports · 2014Article
- Rectal cancer staging: focus on the prognostic significance of the findings described by high-resolution magnetic resonance imaging.Cancer imaging : the official publication of the International Cancer Imaging Society · 2013Review
- The management of rectal cancer with synchronous liver metastases: a modern surgical dilemma.Techniques in coloproctology · 2013Review
- Is there a role for simultaneous hepatic and colorectal resections? A contemporary view from NSQIP.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2012Article
- Current state of surgical treatment of liver metastases from colorectal cancer.World journal of gastrointestinal surgery · 2011Article
- Colorectal liver metastases.International journal of surgical oncology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal strategy for the treatment of synchronous colorectal liver metastases has not been established yet. In this study, we present the outcomes and survival rates of the patients who underwent simultaneous or delayed resections.
methodsWe performed a retrospective analysis of liver resections in our institution between 1997 and 2006.
resultsAmong the 89 patients presenting with synchronous colorectal liver metastases, 28 underwent simultaneous and 61 underwent delayed resection. Age, sex and localization of the primary tumour were similar in the 2 groups. Duration of surgery and hospital stay were longer in the simultaneous resection group, and blood loss was also greater in this group. However, these factors did not influence the frequency of complications, which did not differ between the groups. When we included data from initial colectomy, these differences were either not significant or in favour of synchronous resection. In the delayed resection group, colon resection was performed in different hospitals. The 1-, 3- and 5-year survival rates were 78%, 70% and 45%, respectively, in the simultaneous and 88%, 55% and 38%, respectively, in the delayed resection groups.
conclusionIn select patients, the risk of simultaneous resection of synchronous colorectal liver metastases is comparable to delayed resection, and increases in blood loss and operating time associated with simultaneous resections do not have a negative influence on long-term outcome. Positive outcomes of simultaneous liver resections in our study could be a result of good patient selection or experience with oncological liver surgery.
Indexed as
Identifiers
20011158PMC2792389What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.