ReviewInternational journal of biological sciences2009
Physiological and oncogenic Aurora-A pathway.
Review in International journal of biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Synthesis, molecular modelling and evaluation of (-)-isopulegol-based 2,4-diaminopyrimidines as promising aurora kinase inhibitors.RSC medicinal chemistry · 2026Article
- Integrated Bioinformatic Analysis Reveals the Oncogenic, Survival, and Prognostic Characteristics of TPX2 in Hepatocellular Carcinoma.Biochemical genetics · 2025Article
- Review
- The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review.Cancer cell international · 2020Review
- Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma.Molecular carcinogenesis · 2019Article
- [The function of Aurora A and its role in the development of liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2017Article
- Article
- WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis.Oncogene · 2015Article
- Translational biology of osteosarcoma.Nature reviews. Cancer · 2014Review
- Tyrosine kinase receptors as molecular targets in pheochromocytomas and paragangliomas.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2014Article
- Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma.British journal of cancer · 2013Article
- The role of Aurora A in hypoxia-inducible factor 1α-promoting malignant phenotypes of hepatocelluar carcinoma.Cell cycle (Georgetown, Tex.) · 2013Article
- Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.Molecular oncology · 2013Article
- Current and future trials of targeted therapies in cutaneous melanoma.Advances in experimental medicine and biology · 2013Review
- Development of o-chlorophenyl substituted pyrimidines as exceptionally potent aurora kinase inhibitors.Journal of medicinal chemistry · 2012Article
- Sensitization of tumor cells to cancer therapy by molecularly targeted inhibition of the inhibitor of nuclear factor κB kinase.Translational cancer research · 2012Article
- SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.Cancer cell · 2011Article
- Cyclin B1 expression regulated by cytoplasmic polyadenylation element binding protein in astrocytes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells.PloS one · 2011Article
- Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A.Genes & development · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Aurora family of protein kinases have emerged as crucial factors of, not only mitosis and cytokinesis, but also human carcinogenesis. Among these family members is Aurora-A that is frequently overexpressed in varieties of human cancer. Both in vitro and in vivo studies demonstrated that Aurora-A induces tumorigenesis through genome instability. These studies have further shown that cell signaling cross-talk between Aurora-A and other cellular proteins are essential for fully-transformed phenotypes. This review summarizes recent progress of Aurora-A-associated carcinogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.