Evidence map›Paper›PMID 20010900›Full record

ArticleInternational journal of obesity (2005)2010

Salivary habituation to food stimuli in successful weight loss maintainers, obese and normal-weight adults.

D S Bond, H A Raynor, J M McCaffery, R R Wing

Registry-linked trialAbstract read
In one paragraph

Article in International journal of obesity (2005), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04027426 (Families Becoming Healthy Together), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04027426 nacompletednot on this mapstarted 2019, after this paper: background citation

Families Becoming Healthy Together

TypeinterventionalSponsorThe University of Tennessee, KnoxvilleRan2019 to 2025Enrolled83ConditionsObesity, Childhood ObesityArmsFBT, FBT+Variety
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Variety, palatability, and obesity.Advances in nutrition (Bethesda, Md.) · 2014
    Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D S BondDepartment of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University/The Miriam Hospital, Weight Control and Diabetes Research Center, Providence, RI 02903, USA. dbond@lifespan.org
H A Raynor
J M McCaffery
R R Wing

Funding

Long-Term Weight Loss Maintenance (RMI)R01DK066787 · NIDDK · MIRIAM HOSPITAL · PI WING, RENA R · 2004 to 2007
$1.6M
Increasing Physical Activity Among Inactive Bariatric Surgery PatientsK01DK083438 · NIDDK · MIRIAM HOSPITAL · PI BOND, DALE S · 2009 to 2013
$654k
NIDDK NIH HHS DK066787-02S2NIDDK NIH HHS DK083438-01NIDDK NIH HHS K01 DK083438NIDDK NIH HHS R01 DK066787
6 · The paper itself

Abstract

objectiveResearch shows that slower habituation of salivary responses to food stimuli is related to greater energy intake and that obese (Ob) individuals habituate slower than those of normal weight (NW). No study has examined habituation rates in weight loss maintainers (WLMs) who have reduced from obese to normal weight, relative to those who are Ob or NW.

designSalivation to two baseline water trials and 10 lemon-flavored lollipop trials were studied in 14 WLMs, 15 Ob and 18 NW individuals comparable in age, gender and ethnicity. Linear mixed models were used to compare WLMs with Ob and NW groups.

resultsSalivation in the WLM and NW groups decreased significantly (for both P <0.005) across trials, indicative of habituation. Salivary responses in the Ob group did not habituate (P=0.46). When compared with Ob group, WLMs showed a quicker reduction in salivation (P<0.05). WLM and NW groups did not differ in habituation rate (P=0.49).

conclusionsWLMs have habituation rates that are comparable to NW individuals without previous history of obesity, and show quicker habituation than those who are currently obese. These results suggest that physiological responses to food may 'normalize' with successful weight loss maintenance.

Indexed as

FoodAdultAgedBody WeightFeeding BehaviorFemaleHabituation, PsychophysiologicHumansMaleMiddle AgedObesitySalivationSatiationWeight Loss

Identifiers

PMID20010900
PMCPMC5319213

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.