ArticleRetina (Philadelphia, Pa.)2010
Central retinal vein occlusion in a young Chinese population: risk factors and associated morbidity and mortality.
Article in Retina (Philadelphia, Pa.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Associations of retinal artery occlusion and retinal vein occlusion to mortality, stroke, and myocardial infarction: a systematic review.Eye (London, England) · 2016Pooled it
- Ranibizumab for Macular Edema Secondary to Central and Branch Retinal Vein Occlusion in Patients Younger Than 50 Years of Age.BioMed research international · 2020Trial
- Large-scale analysis of risk factors for developing retinal vein occlusion in the fellow eye.Eye (London, England) · 2026Article
- Comparison of Intravitreal Dexamethasone Implant and Intravitreal Ranibizumab Efficacy in Younger Patients with Branch Retinal Vein Occlusion.Beyoglu eye journal · 2023Article
- Comparison of Each Retinal Layer Thicknesses between Eyes with Central Retinal Vein Occlusion and Normal Contralateral Eyes.Korean journal of ophthalmology : KJO · 2022Article
- Baseline clinical features predict visual outcome in young patients with central retinal vein occlusion.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Central retinal venous occlusion in a child with hyperhomocysteinemia: A case report.Medicine · 2019Article
- Clinical efficacy evaluation of treatment of different degrees of retinal vein occlusion with ranibizumab combined with an argon ion laser.Experimental and therapeutic medicine · 2019Article
- Combined Central Retinal Vein And Artery Occlusion In A Patient With Elevated Level Of Factor VIII: A Case Report.International medical case reports journal · 2019Article
- Central Retinal Vein Occlusion in Younger Swedish Adults: Case Reports and Review of the Literature.The open ophthalmology journal · 2017Article
- Retinal artery and vein thrombotic occlusion during pregnancy: markers for familial thrombophilia and adverse pregnancy outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2016Article
- Intense exercise causing central retinal vein occlusion in a young patient: case report and review of the literature.Case reports in ophthalmology · 2014Article
- A longitudinal analysis of risk factors associated with central retinal vein occlusion.Ophthalmology · 2013Article
- Thrombophilia and retinal vascular occlusion.Clinical ophthalmology (Auckland, N.Z.) · 2012Article
- Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors.Molecular vision · 2011Article
- Prevalence and risk factors of retinal vein occlusion in individuals with diabetes: The kailuan eye study.Diabetes & vascular disease researchArticle
- Unilateral central retinal vein occlusion as a first manifestation of diabetes mellitus in a ten-year-old girl.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe purpose of this study was to assess the risk factors for central retinal vein occlusion and associated morbidity and mortality in a Chinese population.
methodsThe participants included patients with central retinal vein occlusion 40 years old and younger. Predisposing factors, mortality, and systemic complications were examined in this group.
resultsUnilateral (n = 19) and bilateral (n = 3) central retinal vein occlusions were identified in a total of 22 patients (25 eyes), with a mean follow-up time of 37 months. Hypercholesterolemia (65%), hypertriglyceridemia (64%), and hyperhomocysteinemia (42%) were all identified as risk factors. Three patients (14%) developed stroke and 1 (5%) developed transient ischemic attacks during follow-up. Renal failure and pulmonary hypertension resulted in the death of two patients. The mean initial and final visual acuities (+ or - standard deviation) were 20/400 (+ or - 20/250) and 20/500 (+ or - 20/320), respectively, and treatments did not result in vision improvement (P = 0.57). The poor visual prognosis was likely due to macular edema in 7 eyes (28%), optic atrophy in 4 eyes (16%), and secondary glaucoma in 3 eyes (12%).
conclusionMorbidity and mortality are high in young Chinese patients with central retinal vein occlusion who may have associated serious complications including stroke, blindness, and death. Central retinal vein occlusion may serve as an initial clinical presentation of serious systemic diseases.
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Registered trials
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