ArticleJAMA2009
Late-life dementias: does this unyielding global challenge require a broader view?
Article in JAMA, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03277573 (A Phase 1b, 12-Month, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Salsalate in Patients With Mild to Moderate Alzheimer's Disease), which is not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase 1b, 12-Month, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Salsalate in Patients With Mild to Moderate Alzheimer's Disease
Who cites it
12 citing papers in PubMed.
- Leveraging neuropathological data in pharmacoepidemiology: A promising approach for dementia prevention?Pharmacoepidemiology and drug safety · 2021Article
- Proposal Guidelines for Standardized Operating Procedures of Brain Autopsy: Brain Bank in South Korea.Yonsei medical journal · 2017Article
- Recent Progress in Alzheimer's Disease Research, Part 3: Diagnosis and Treatment.Journal of Alzheimer's disease : JAD · 2017Review
- Somatic comorbidities and Alzheimer's disease treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013Article
- The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier).Alzheimer's & dementia : the journal of the Alzheimer's Association · 2013Review
- Anatomic and clinical pathology of cognitive impairment and dementia.Journal of Alzheimer's disease : JAD · 2013Review
- National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2012Article
- Role of cerebrospinal fluid and plasma biomarkers in the diagnosis of neurodegenerative disorders and mild cognitive impairment.Current neurology and neuroscience reports · 2011Review
- Ecology of the aging human brain.Archives of neurology · 2011Article
- Elevated natriuretic peptide levels and cognitive function in community-dwelling older adults.The American journal of medicine · 2011Article
- Histamine-2 receptor antagonist use and incident dementia in an older cohort.Journal of the American Geriatrics Society · 2011Article
- Prospects for delaying the rising tide of worldwide, late-life dementias.International psychogeriatrics · 2010Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.