ArticleBMJ (Clinical research ed.)2009
Perceived age as clinically useful biomarker of ageing: cohort study.
Article in BMJ (Clinical research ed.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Perceived Age as a Mortality and Comorbidity Predictor: A Systematic Review.Aesthetic plastic surgery · 2023Pooled it
- Trial
- Perinatal complications and aging indicators by midlife.Pediatrics · 2014Trial
- Is looking older than one's actual age a sign of poor health?Journal of general internal medicine · 2011Trial
- Facial skin aging: an integrative analysis of genetics, epigenetics, and lifestyle factors.GeroScience · 2026Article
- Dermal fibroblasts cultured from aged human skin display a pro-inflammatory phenotype.Journal of cell communication and signaling · 2026Article
- TRF2 Recovers Ischemic Postconditioning Cardioprotection in Aged Myocardiocytes by Regulating CSNK2A2 Localization and FUNDC1 Dephosphorylation.Aging cell · 2026Article
- A new framework for facial age estimation in humans and AIs.Scientific reports · 2026Article
- There Are Multiple Clocks That Time Us: Cross-Sectional and Longitudinal Associations Among 14 Alternative Indicators of Age and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- IncreasedGeroScience · 2025Article
- [The impact of diabetes on aesthetic procedures].Dermatologie (Heidelberg, Germany) · 2025Review
- Identification of gene-sun exposure interactions of GWAS-identified variants in perceived facial aging progression.Frontiers in aging · 2025Article
- Perceived age estimation from facial image and demographic data in young and middle-aged South Korean adults.Scientific reports · 2024Article
- Deep learning predicted perceived age is a reliable approach for analysis of facial ageing: A proof of principle study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2024Article
- Facial aging, cognitive impairment, and dementia risk.Alzheimer's research & therapy · 2024Article
- Using non-invasive behavioral and physiological data to measure biological age in wild baboons.GeroScience · 2024Article
- The association of psychological and trauma-related factors with biological and facial aging acceleration: evidence from the UK Biobank.BMC medicine · 2024Article
- External Testing of a Deep Learning Model to Estimate Biologic Age Using Chest Radiographs.Radiology. Artificial intelligence · 2024Article
- Applications of artificial intelligence in dementia.Geriatrics & gerontology international · 2024Review
- Skinly: A novel handheld IoT device for validating biophysical skin characteristics.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
objectiveTo determine whether perceived age correlates with survival and important age related phenotypes.
designFollow-up study, with survival of twins determined up to January 2008, by which time 675 (37%) had died.
settingPopulation based twin cohort in Denmark.
participants20 nurses, 10 young men, and 11 older women (assessors); 1826 twins aged >or=70.
main outcome measuresAssessors: perceived age of twins from photographs. Twins: physical and cognitive tests and molecular biomarker of ageing (leucocyte telomere length).
resultsFor all three groups of assessors, perceived age was significantly associated with survival, even after adjustment for chronological age, sex, and rearing environment. Perceived age was still significantly associated with survival after further adjustment for physical and cognitive functioning. The likelihood that the older looking twin of the pair died first increased with increasing discordance in perceived age within the twin pair-that is, the bigger the difference in perceived age within the pair, the more likely that the older looking twin died first. Twin analyses suggested that common genetic factors influence both perceived age and survival. Perceived age, controlled for chronological age and sex, also correlated significantly with physical and cognitive functioning as well as with leucocyte telomere length.
conclusionPerceived age-which is widely used by clinicians as a general indication of a patient's health-is a robust biomarker of ageing that predicts survival among those aged >or=70 and correlates with important functional and molecular ageing phenotypes.
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