ReviewHematology. American Society of Hematology. Education Program2009
Drug-induced thrombocytopenia: pathogenesis, evaluation, and management.
Review in Hematology. American Society of Hematology. Education Program, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 2 syntheses or guidelines pooled it, 281 citations in OpenAlex.
- Evaluate Short-Term Outcomes of abciximab in ST-Segment Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Clinical Trials.Journal of interventional cardiology · 2022Pooled it
- A systematic evaluation of laboratory testing for drug-induced immune thrombocytopenia.Journal of thrombosis and haemostasis : JTH · 2013Pooled it
- Immune thrombocytopenia in alemtuzumab-treated MS patients: Incidence, detection, and management.Multiple sclerosis (Houndmills, Basingstoke, England) · 2020Trial
- Antiepileptic drug therapy in companion animals: New perspectives on clinical pathology monitoring.Veterinary and animal science · 2026Review
- Real-time active surveillance for drug-induced Thrombocytopenia: A prospective interventional study.Exploratory research in clinical and social pharmacy · 2026Article
- Severe immune thrombocytopenia induced by vancomycin in a critically ill patient: a case report and literature review.Thrombosis journal · 2026Article
- Fulminant drug-induced immune thrombocytopenia in polycystic kidney disease with cyst infection.CEN case reports · 2026Article
- Pharmacovigilance and clinical insights into perindopril-induced thrombocytopenia: a case report of diagnostic challenges and therapeutic alternatives.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Intravenous Thiamine-Induced Thrombocytopenia in a Patient With Chronic Adrenal Insufficiency.Journal of medical cases · 2026Article
- Case report: Butylphthalide-associated severe thrombocytopenia, a rare adverse drug reaction.Frontiers in pharmacology · 2026Article
- Unveiling meropenem-induced thrombocytopenia: Insight from a positive rechallenge case.IDCases · 2026Article
- Sodium Valproate-Associated Thrombocytopenia in Antiepileptic Drug Polypharmacy: A Case Report and Review of the Literature.The American journal of case reports · 2025Review
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- The use of systemic immune inflammatory index as a predictor for nematodes infections in horses.Parasite epidemiology and control · 2025Article
- Development and external validation of a machine learning model for predicting drug-induced immune thrombocytopenia in a real-world hospital cohort.BMC medical informatics and decision making · 2025Article
- Article
- Immune Thrombocytopenia Triggered by Sildenafil-Containing Rhino 69 Platinum 1000: A Case Report.Cureus · 2025Article
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- Cellular immune changes during severe antisense oligonucleotide-associated thrombocytopenia in a nonhuman primate model.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Although drugs are a common cause of acute immune-mediated thrombocytopenia in adults, the drug etiology is often initially unrecognized. Most cases of drug-induced thrombocytopenia (DITP) are caused by drug-dependent antibodies that are specific for the drug structure and bind tightly to platelets by their Fab regions but only in the presence of the drug. A comprehensive database of 1301 published reports describing 317 drugs, available at www.ouhsc.edu/platelets, provides information on the level of evidence for a causal relation to thrombocytopenia. Typically, DITP occurs 1 to 2 weeks after beginning a new drug or suddenly after a single dose when a drug has previously been taken intermittently. However, severe thrombocytopenia can occur immediately after the first administration of antithrombotic agents that block fibrinogen binding to platelet GP IIb-IIIa, such as abciximab, tirofiban, and eptifibatide. Recovery from DITP usually begins within 1 to 2 days of stopping the drug and is typically complete within a week. Drug-dependent antibodies can persist for many years; therefore, it is important that the drug etiology be confirmed and the drug be avoided thereafter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.