ArticleJournal of epidemiology and community health2011
Investigating the spatial variability in incidence of coronary heart disease in the Gazel cohort: the impact of area socioeconomic position and mediating role of risk factors.
Article in Journal of epidemiology and community health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Geographic and area-level socioeconomic variation in cardiometabolic risk factor distribution: a systematic review of the literature.International journal of health geographics · 2019Pooled it
- Harnessing Wearables and Digital Technologies to Decode the Cardiovascular Exposome.Methodist DeBakey cardiovascular journal · 2024Review
- Zip Code Health Disparities: Mapping Cardiovascular Inequities at the Neighborhood Level.Methodist DeBakey cardiovascular journal · 2024Review
- The magnitude and importance of perceived health dimensions define effective tailor-made health-promoting interventions per targeted socioeconomic group.Frontiers in public health · 2022Article
- Educational Level, but Not Income or Area Deprivation, is Related to Macrovascular Disease: Results From Two Population-Based Cohorts in Germany.International journal of public health · 2021Article
- Geographic variation in cardiometabolic risk factor prevalence explained by area-level disadvantage in the Illawarra-Shoalhaven region of the NSW, Australia.Scientific reports · 2020Article
- Socio-economic inequalities in life expectancy of older adults with and without multimorbidity: a record linkage study of 1.1 million people in England.International journal of epidemiology · 2019Article
- The association between neighborhood socioeconomic status and clinical outcomes among patients 1 year after hospitalization for cardiovascular disease.Journal of community health · 2013Article
- Neighbourhood socioeconomic inequalities in incidence of acute myocardial infarction: a cohort study quantifying age- and gender-specific differences in relative and absolute terms.BMC public health · 2012Article
- A review of spatial methods in epidemiology, 2000-2010.Annual review of public health · 2012Review
- Towns with extremely low mortality due to ischemic heart disease in Spain.BMC public health · 2012Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectiveThe aim of the study was to improve understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD) incidence in France. Several authors have suggested that CHD risk factors (diabetes, hypertension, cholesterol, overweight, tobacco consumption) may partly mediate associations between socioeconomic environmental variables and CHD. Studies have assessed the overall mediating role of CHD risk factors, but have never investigated the specific mediating role of each risk factor, not allowing their specific contribution to the area socioeconomic position-CHD association to be disentangled.
designAfter assessing geographical variations in CHD incidence and socioeconomic environmental effects on CHD using a multilevel Cox model, the extent to which this contextual effect was mediated by each of the CHD risk factors was assessed.
participantsData of the French GAZEL cohort (n=19,808) were used. MAIN
resultsAfter adjustment for several individual socioeconomic indicators, it was found, in men from highly urbanised environments, that CHD incidence increased with decreasing socioeconomic position of the residential environment. After individual-level adjustment, a higher risk of obesity, smoking and cholesterol was observed in the most deprived residential environments. When risk factors were introduced into the model, a modest decrease was observed in the magnitude of the association between the socioeconomic contextual variable and CHD. Risk factors that contributed most to the decrease of the association were smoking and cholesterol.
conclusionsClassic risk factors, although some of them more than others, mediated a modest part of the association between area socioeconomic position and CHD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.