ArticlePlant physiology2010
A Raf-like MAPKKK gene DSM1 mediates drought resistance through reactive oxygen species scavenging in rice.
Article in Plant physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers.
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161 citing papers in PubMed, 385 citations in OpenAlex.
- A TaMYB2-TaMAP3K17 module enhances drought tolerance by promoting reactive oxygen species scavenging in wheat.aBIOTECH · 2026Article
- PuCBL9-PuCIPK11 Modulates Stomatal Microfilament Reorganisation in a Phosphorylation-Dependent Manner to Enhance Drought Tolerance in Poplar.Plant, cell & environment · 2026Article
- Identification of salt-responsive mitogen-activated protein kinase cascade members in the halophyte N. sibirica.BMC plant biology · 2026Article
- Reactive Oxygen Species in Crop Plants: Production, Detoxification, Signaling, and Molecular Cross-Talk.Plants (Basel, Switzerland) · 2026Review
- Exogenous porcine blood polypeptide alleviates drought damage in wheat.BMC plant biology · 2026Article
- Arbuscular mycorrhizal fungi as integrative modulators of plant tolerance to drought, salinity, and heavy metal stress: mechanistic insights and future directions.Journal, genetic engineering & biotechnology · 2026Review
- Genome-Wide Identification Analysis of the MAPKKK Gene Family in Cotton and Its Role in Development and Stress Response.International journal of molecular sciences · 2026Article
- GmMEKK2 Disrupts the MKK1/2-MPK4 Cascade to Amplify Immune Signalling and Confer Enhanced Resistance to Soybean Mosaic Virus.Molecular plant pathology · 2025Article
- Priming with Porcine Blood Polypeptide Enhances Salt Tolerance in Wheat Seedlings.Plants (Basel, Switzerland) · 2025Article
- Integrative transcriptomics and metabolomics analyses reveals Maillard reaction and antioxidant capacity-mediated leaf Browning during the flue-curing process in Nicotiana tabacum L.BMC plant biology · 2025Article
- Genomic introgression underlies environmental adaptation in three species of Chinese wingnuts,Plant diversity · 2025Article
- OsMAPKKK5 affects brassinosteroid signal transduction via phosphorylating OsBSK1-1 and regulates rice plant architecture and yield.Plant biotechnology journal · 2025Article
- Nei 6 You 7075, a hybrid rice cultivar, exhibits enhanced disease resistance and drought tolerance traits.BMC plant biology · 2024Article
- Review
- Multifunctional Transcription Factor YABBY6 Regulates Morphogenesis, Drought and Cold Stress Responses in Rice.Rice (New York, N.Y.) · 2024Article
- Involvement of the Metallothionein gene OsMT2b in Drought and Cadmium Ions Stress in Rice.Rice (New York, N.Y.) · 2024Article
- Enhancing Coleoptile Length of Rice Seeds under Submergence throughPlants (Basel, Switzerland) · 2024Article
- Article
- Overexpression of OsNAR2.1 by OsNAR2.1 promoter increases drought resistance by increasing the expression of OsPLDα1 in rice.BMC plant biology · 2024Article
- Hydrogen Sulfide Alleviates Oxidative Damage under Chilling Stress through Mitogen-Activated Protein Kinase in Tomato.Antioxidants (Basel, Switzerland) · 2024Article
101 more citing papers are in PubMed but not listed here.
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4 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Mitogen-activated protein kinase (MAPK) cascades have been identified in various signaling pathways involved in plant development and stress responses. We identified a drought-hypersensitive mutant (drought-hypersensitive mutant1 [dsm1]) of a putative MAPK kinase kinase (MAPKKK) gene in rice (Oryza sativa). Two allelic dsm1 mutants were more sensitive than wild-type plants to drought stress at both seedling and panicle development stages. The dsm1 mutants lost water more rapidly than wild-type plants under drought stress, which was in agreement with the increased drought-sensitivity phenotype of the mutant plants. DSM1-RNA interference lines were also hypersensitive to drought stress. The predicted DSM1 protein belongs to a B3 subgroup of plant Raf-like MAPKKKs and was localized in the nucleus. By real-time PCR analysis, the DSM1 gene was induced by salt, drought, and abscisic acid, but not by cold. Microarray analysis revealed that two peroxidase (POX) genes, POX22.3 and POX8.1, were sharply down-regulated compared to wild type, suggesting that DSM1 may be involved in reactive oxygen species (ROS) signaling. Peroxidase activity, electrolyte leakage, chlorophyll content, and 3,3'-diaminobenzidine staining revealed that the dsm1 mutant was more sensitive to oxidative stress due to an increase in ROS damage caused by the reduced POX activity. Overexpression of DSM1 in rice increased the tolerance to dehydration stress at the seedling stage. Together, these results suggest that DSM1 might be a novel MAPKKK functioning as an early signaling component in regulating responses to drought stress by regulating scavenging of ROS in rice.
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