ArticleNeuroscience2010
Projections from auditory cortex to midbrain cholinergic neurons that project to the inferior colliculus.
Article in Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Age-related ultrastructural differences in the dorsal cortex of the inferior colliculus in the fischer brown Norway rat.Neurobiology of aging · 2026Article
- Characterization of three cholinergic inputs to the cochlear nucleus.Journal of chemical neuroanatomy · 2023Article
- Changes in the Gene Expression Profiles of the Inferior Colliculus Following Unilateral Cochlear Ablation in Adult Rats.Biochemical genetics · 2021Article
- Phasic activation of the locus coeruleus attenuates the acoustic startle response by increasing cortical arousal.Scientific reports · 2021Article
- αFrontiers in neural circuits · 2021Article
- Circuit Mechanisms Underlying the Segregation and Integration of Parallel Processing Streams in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- A Cortico-Collicular Amplification Mechanism for Gap Detection.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Cholinergic Projections From the Pedunculopontine Tegmental Nucleus Contact Excitatory and Inhibitory Neurons in the Inferior Colliculus.Frontiers in neural circuits · 2020Article
- The pedunculopontine tegmental nucleus-A functional hypothesis from the comparative literature.Movement disorders : official journal of the Movement Disorder Society · 2016Review
- Benefits of Stimulus Exposure: Developmental Learning Independent of Task Performance.Frontiers in neuroscience · 2016Article
- Cholinergic Modulation of Stimulus-Specific Adaptation in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Differences in the strength of cortical and brainstem inputs to SSA and non-SSA neurons in the inferior colliculus.Scientific reports · 2015Article
- Lentivirus-mediated delivery of sonic hedgehog into the striatum stimulates neuroregeneration in a rat model of Parkinson disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2014Article
- Analysis of excitatory synapses in the guinea pig inferior colliculus: a study using electron microscopy and GABA immunocytochemistry.Neuroscience · 2013Article
- Tonotopic and localized pathways from primary auditory cortex to the central nucleus of the inferior colliculus.Frontiers in neural circuits · 2013Article
- Differentially organized top-down modulation of prepulse inhibition of startle.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Cholinergic cells of the pontomesencephalic tegmentum: connections with auditory structures from cochlear nucleus to cortex.Hearing research · 2011Review
- Knowledge synthesis with maps of neural connectivity.Frontiers in neuroinformatics · 2011Article
- Why would Musical Training Benefit the Neural Encoding of Speech? The OPERA Hypothesis.Frontiers in psychology · 2011Article
- Cholinergic and non-cholinergic projections from the pedunculopontine and laterodorsal tegmental nuclei to the medial geniculate body in Guinea pigs.Frontiers in neuroanatomy · 2010Article
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Abstract
We have shown that auditory cortex projects to cholinergic cells in the pedunculopontine tegmental nucleus (PPT) and laterodorsal tegmental nucleus (LDT). PPT and LDT are the sources of cholinergic projections to the inferior colliculus, but it is not known if the cortical inputs contact the cholinergic cells that project to the inferior colliculus. We injected FluoroRuby into auditory cortex in pigmented guinea pigs to label cortical projections to PPT and LDT. In the same animals, we injected Fast Blue into the left or right inferior colliculus to label PPT and LDT cells that project to the inferior colliculus. We processed the brain to identify cholinergic cells with an antibody to choline acetyltransferase, which was visualized with a green fluorescent marker distinguishable from both FluoroRuby and Fast Blue. We then examined the PPT and LDT to determine whether boutons of FluoroRuby-labeled cortical axons were in close contact with cells that were double-labeled with the retrograde tracer and the immunolabel. Apparent contacts were observed ipsilateral and, less often, contralateral to the injected cortex. On both sides, the contacts were more numerous in PPT than in LDT. The results indicate that auditory cortex projects directly to brainstem cholinergic cells that innervate the ipsilateral or contralateral inferior colliculus. This suggests that cortical projections could elicit cholinergic effects on both sides of the auditory midbrain.
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