ReviewTrends in cell biology2010
Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function.
Review in Trends in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 77 citations in OpenAlex.
- RNA Pol II Assembly Affects ncRNA Expression.International journal of molecular sciences · 2023Article
- Alternative Splicing in the Regulatory Circuit of Plant Temperature Response.International journal of molecular sciences · 2023Review
- Small ORFs as New Regulators of Pri-miRNAs and miRNAs Expression inInternational journal of molecular sciences · 2022Article
- Wrong place, wrong time: Runt-related transcription factor 2/SATB2 pathway in bone development and carcinogenesis.Journal of carcinogenesis · 2021Review
- Article
- Emerging roles of DROSHA beyond primary microRNA processing.RNA biology · 2018Article
- DROSHA targets its own transcript to modulate alternative splicing.RNA (New York, N.Y.) · 2017Article
- Polyadenylated tail length variation pattern in ultra-rapid vitrified bovine oocytes.Veterinary world · 2016Article
- Article
- Primary microRNA processing is functionally coupled to RNAP II transcription in vitro.Scientific reports · 2015Article
- Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein.International journal of molecular sciences · 2015Article
- Mechanisms and Regulation of Alternative Pre-mRNA Splicing.Annual review of biochemistry · 2015Review
- Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome.Nucleic acids research · 2014Article
- Dopaminergic tone persistently regulates voltage-gated ion current densities through the D1R-PKA axis, RNA polymerase II transcription, RNAi, mTORC1, and translation.Frontiers in cellular neuroscience · 2014Article
- c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2.The Journal of biological chemistry · 2013Article
- Reversible RNA adenosine methylation in biological regulation.Trends in genetics : TIG · 2013Review
- MicroRNAs and DNA damage response: implications for cancer therapy.Cell cycle (Georgetown, Tex.) · 2013Review
- Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression.Genes & development · 2012Article
- The RNA polymerase II CTD coordinates transcription and RNA processing.Genes & development · 2012Review
- Sex differences in microRNA regulation of gene expression: no smoke, just miRs.Biology of sex differences · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The expression of protein-coding genes is enhanced by the exquisite coupling of transcription by RNA polymerase II with pre-messenger RNA processing reactions, such as 5'-end capping, splicing and 3'-end formation. Integration between cotranscriptional processing events extends beyond the nucleus, as proteins that bind cotranscriptionally can affect the localization, translation and degradation of the mature messenger RNA. MicroRNAs are RNA polymerase II transcripts with crucial roles in the regulation of gene expression. Recent data demonstrate that processing of primary microRNA transcripts might be yet another cotranscriptional event that is woven into this elaborate nuclear network. This review discusses the extensive molecular interactions that couple the earliest steps in gene expression and therefore influence the final fate and function of the mature messenger RNA or microRNA produced.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.