Evidence map›Paper›PMID 20003924›Full record

Trial reportVaccine2010

Impact of influenza-like illness and effectiveness of influenza vaccination in oncohematological children who have completed cancer therapy.

Susanna Esposito, Valerio Cecinati, Barbara Scicchitano, Giovanni Carlo Delvecchio, Nicola Santoro, Doriana Amato, Claudio Pelucchi, Momcilo Jankovic, Domenico De Mattia, Nicola Principi

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Vaccine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Immunization of children with secondary immunodeficiency.Human vaccines & immunotherapeutics · 2015
    Review
  9. Adult Acute Myeloid Leukemia Long-term Survivors.Journal of leukemia (Los Angeles, Calif.) · 2014
    Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Susanna EspositoDepartment of Maternal and Pediatric Sciences, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regine Elena, Via Commenda 9, 20122 Milan, Italy.
Valerio Cecinati
Barbara Scicchitano
Giovanni Carlo Delvecchio
Nicola Santoro
Doriana Amato
Claudio Pelucchi
Momcilo Jankovic
Domenico De Mattia
Nicola Principi
University of Bari Aldo Moro · ITUniversity of Milano-Bicocca · ITMario Negri Institute for Pharmacological Research · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to evaluate the impact of influenza-like illness and the effectiveness of influenza vaccination in children with oncohematological disease who have completed cancer therapy, 182 children with a diagnosis of oncohematological disease were divided into two subgroups on the basis of the length of time off therapy (<6 months or 6-24 months) and randomised 1:1 to receive influenza vaccination or not. The controls were 91 otherwise healthy children unvaccinated against influenza. The results show that the clinical and socioeconomic impact of influenza-like illnesses and the effectiveness of influenza vaccination in oncohematological children who have completed cancer therapy are related to the length of the off therapy period, and seem to be significantly greater in those who have been off therapy for less than 6 months in comparison with healthy controls. This suggests that the administration of influenza vaccination should be strongly recommended only among oncohematological children who have been off therapy for less than 6 months.

Indexed as

AdolescentAntineoplastic AgentsChildChild, PreschoolFemaleHematologic NeoplasmsHumansImmunocompromised HostInfluenza, HumanInfluenza VaccinesMalePrevalenceTime FactorsAntineoplastic AgentsInfluenza Vaccines

Identifiers

PMID20003924
PMCPMC7172348
OpenAlexW2087264252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.