ArticleBMC family practice2009
Gender differences in presentation and diagnosis of chest pain in primary care.
Article in BMC family practice, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- Exploring the use of AI-generated counterfactual chest X-rays to enhance diagnostic learning in medical education.BMC medical education · 2026Article
- Sex-specific angiographic findings and clinical features in patients with myocardial infarction.Scientific reports · 2025Article
- Can the Location of Angina Predict the Site of Coronary Artery Occlusion in Acute Myocardial Infarction? - The ACOLYTE Study.Journal of the Saudi Heart Association · 2025Article
- Sex differences in patterns of referral and resource utilization in the cardiology clinic: an outpatient analysis.Frontiers in cardiovascular medicine · 2023Article
- A retrospective analysis of gender among patients admitted to a clinical decision unit at risk for acute coronary syndrome.World journal of emergency medicine · 2023Article
- Complicated myocardial infarction in a 99-year-old lady in the era of COVID-19 pandemic: from the need to rule out coronavirus infection to emergency percutaneous coronary angioplasty.Internal and emergency medicine · 2020Article
- Gender differences in the presentation of chest pain in obstructive coronary artery disease: results from the Korean Women's Chest Pain Registry.The Korean journal of internal medicine · 2020Article
- Observational
- Observational
- Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States.The American journal of cardiology · 2017Article
- The cost-utility of point-of-care troponin testing to diagnose acute coronary syndrome in primary care.BMC cardiovascular disorders · 2017Article
- Chronic symptoms in a representative sample of community-dwelling older people: a cross-sectional study in Switzerland.BMJ open · 2017Article
- Incidence of and Predictors for Early Return Visits to the Emergency Department: A Population-Based Survey.Medicine · 2015Article
- Article
- Chest Pain as a presenting complaint in patients with acute myocardial infarction (AMI).Pakistan journal of medical sciences · 2013Article
- Elevated PLA2G7 gene promoter methylation as a gender-specific marker of aging increases the risk of coronary heart disease in females.PloS one · 2013Article
- Development and validation of a clinical prediction rule for chest wall syndrome in primary care.BMC family practice · 2012Article
- The diagnosis of coronary heart disease in a low-prevalence setting: follow-up data from patients whose CHD was misdiagnosed by their family doctors.Deutsches Arzteblatt international · 2011Article
- Gender bias revisited: new insights on the differential management of chest pain.BMC family practice · 2011Article
- Recent advances in the management of chronic stable angina I: approach to the patient, diagnosis, pathophysiology, risk stratification, and gender disparities.Vascular health and risk management · 2010Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChest pain is a common complaint and reason for consultation in primary care. Research related to gender differences in regard to Coronary Heart Disease (CHD) has been mainly conducted in hospital but not in primary care settings. We aimed to analyse gender differences in aetiology and clinical characteristics of chest pain and to provide gender related symptoms and signs associated with CHD.
methodsWe included 1212 consecutive patients with chest pain aged 35 years and older attending 74 general practitioners (GPs). GPs recorded symptoms and findings of each patient and provided follow up information. An independent interdisciplinary reference panel reviewed clinical data of every patient and decided about the aetiology of chest pain at the time of patient recruitment. Multivariable regression analysis was performed to identify clinical predictors that help to rule in or out CHD in women and men.
resultsWomen showed more psychogenic disorders (women 11,2%, men 7.3%, p = 0.02), men suffered more from CHD (women 13.0%, men 17.2%, p = 0.04), trauma (women 1.8%, men 5.1%, p < 0.001) and pneumonia/pleurisy (women 1.3%, men 3.0%, p = 0.04) Men showed significantly more often chest pain localised on the right side of the chest (women 9.1%, men 25.0%, p = 0.01). For both genders known clinical vascular disease, pain worse with exercise and age were associated positively with CHD. In women pain duration above one hour was associated positively with CHD, while shorter pain durations showed an association with CHD in men. In women negative associations were found for stinging pain and in men for pain depending on inspiration and localised muscle tension.
conclusionsWe found gender differences in regard to aetiology, selected clinical characteristics and association of symptoms and signs with CHD in patients presenting with chest pain in a primary care setting. Further research is necessary to elucidate whether these differences would support recommendations for different diagnostic approaches for CHD according to a patient's gender.
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