ArticleBMC genomics2009
Improved tRNA prediction in the American house dust mite reveals widespread occurrence of extremely short minimal tRNAs in acariform mites.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 79 citations in OpenAlex.
- First report of mitochondrial genomes in Hydryphantoidea: novel genomes, evolution rate, and gene rearrangement patterns in two water mites (Acari: Hydrachnidia).Experimental & applied acarology · 2026Article
- Comparative study on morphological traits and mitogenomes of the genus Echinolaelaps.Experimental & applied acarology · 2026Article
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- The complete mitochondrial genome analysis ofOpen life sciences · 2025Article
- Aberrant Mitochondrial tRNA Genes Appear Frequently in Animal Evolution.Genome biology and evolution · 2024Article
- Mitochondrial metagenomics reveal the independent colonization of the world's coasts by intertidal oribatid mites (Acari, Oribatida, Ameronothroidea).Scientific reports · 2024Article
- A Chromosomal-Level Genome ofInternational journal of genomics · 2024Article
- Diversity and Distribution of Mites (ACARI) Revealed by Contamination Survey in Public Genomic Databases.Animals : an open access journal from MDPI · 2023Article
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- Complete mitochondrial genomes of Thyreophagus entomophagus and Acarus siro (Sarcoptiformes: Astigmatina) provide insight into mitogenome features, evolution, and phylogeny among Acaroidea mites.Experimental & applied acarology · 2022Review
- Mitochondrial analysis of oribatid mites provides insights into their atypical tRNA annotation, genome rearrangement and evolution.Parasites & vectors · 2021Article
- Hopeful monsters: unintended sequencing of famously malformed mite mitochondrial tRNAs reveals widespread expression and processing of sense-antisense pairs.NAR genomics and bioinformatics · 2021Article
- Adaptation of theInternational journal of molecular sciences · 2020Article
- De novo sequence of the mitochondrial genome of Tyrophagus putrescentiae (Acari: Sarcoptiformes) including 22 tRNA sequences and the largest non-coding region.Experimental & applied acarology · 2020Article
- Naturally Occurring tRNAs With Non-canonical Structures.Frontiers in microbiology · 2020Review
- Article
- Article
- Population and Culture Age Influence the Microbiome Profiles of House Dust Mites.Microbial ecology · 2019Article
- Small but large enough: structural properties of armless mitochondrial tRNAs from the nematode Romanomermis culicivorax.Nucleic acids research · 2018Article
- The mitochondrial genomes of sarcoptiform mites: are any transfer RNA genes really lost?BMC genomics · 2018Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtypical tRNAs are functional minimal tRNAs, lacking either the D- or T-arm. They are significantly shorter than typical cloverleaf tRNAs. Widespread occurrence of atypical tRNAs was first demonstrated for secernentean nematodes and later in various arachnids. Evidence started to accumulate that tRNAs of certain acariform mites are even shorter than the minimal tRNAs of nematodes, raising the possibility that tRNAs lacking both D- and T-arms might exist in these organisms. The presence of cloverleaf tRNAs in acariform mites, particularly in the house dust mite genus Dermatophagoides, is still disputed.
resultsMitochondrial tRNAs of Dermatophagoides farinae are minimal, atypical tRNAs lacking either the T- or D-arm. The size (49-62, 54.4 +/- 2.86 nt) is significantly (p = 0.019) smaller than in Caenorhabditis elegans (53-63, 56.3 +/- 2.30 nt), a model minimal tRNA taxon. The shortest tRNA (49 nt) in Dermatophagoides is approaching the length of the shortest known tRNAs (45-49 nt) described in other acariform mites. The D-arm is absent in these tRNAs, and the inferred T-stem is small (2-3 bp) and thermodynamically unstable, suggesting that it may not exist in reality. The discriminator nucleotide is probably not encoded and is added postranscriptionally in many Dermatophagoides tRNAs.
conclusionsMitochondrial tRNAs of acariform mites are largely atypical, non-cloverleaf tRNAs. Among them, the shortest known tRNAs with no D-arm and a short and unstable T-arm can be inferred. While our study confirmed seven tRNAs in Dermatophagoides by limited EST data, further experimental evidence is needed to demonstrate extremely small and unusual tRNAs in acariform mites.
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