Trial reportRespiratory research2009
Dietary intake, lung function and airway inflammation in Mexico City school children exposed to air pollutants.
Trial report in Respiratory research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Does adherence to the Mediterranean dietary pattern reduce asthma symptoms in children? A systematic review of observational studies.Public health nutrition · 2017Pooled it
- Effects of Fruit and Vegetable Consumption on Risk of Asthma, Wheezing and Immune Responses: A Systematic Review and Meta-Analysis.Nutrients · 2017Pooled it
- DASH for asthma: a pilot study of the DASH diet in not-well-controlled adult asthma.Contemporary clinical trials · 2013Trial
- Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study.Respiratory research · 2013Trial
- Maternal dietary pattern during pregnancy is not associated with recurrent wheeze in children.The Journal of allergy and clinical immunology · 2010Trial
- Supplements and medications for respiratory resilience against air pollution.ERJ open research · 2026Review
- Nutrition as a Modifiable Factor in Optimizing Respiratory Health: Evidence from Pulmonary Function Tests.Children (Basel, Switzerland) · 2026Review
- Review
- Effects of Nutritional Education and Diet on Obesity and Asthma Progression in Children and Adolescents.Nutrients · 2025Observational
- Effectiveness of an antioxidant-rich diet on childhood asthma outcomes: A randomized controlled trial.BMC nutrition · 2025Article
- The association between fruit and vegetable intake and the odds of asthma among children and adolescents.Journal of health, population, and nutrition · 2025Article
- Article
- Importance of diet in children and adolescents with obesity and asthma.Pediatric endocrinology, diabetes, and metabolism · 2024Review
- Air Pollution and Diet: Potential Interacting Exposures in Asthma.Current allergy and asthma reports · 2023Review
- Advances in pulmonary rehabilitation for children with bronchial asthma.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2023Review
- Ozone and childhood respiratory health: A primer for US pediatric providers and a call for a more protective standard.Pediatric pulmonology · 2023Review
- Dietary patterns, lung function and asthma in childhood: a longitudinal study.Respiratory research · 2023Article
- Basis of preventive and non-pharmacological interventions in asthma.Frontiers in public health · 2023Review
- Review
- Carbohydrate intake quality and gestational diabetes mellitus, and the modifying effect of air pollution.Frontiers in nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAir pollutant exposure has been associated with an increase in inflammatory markers and a decline in lung function in asthmatic children. Several studies suggest that dietary intake of fruits and vegetables might modify the adverse effect of air pollutants.
methodsA total of 158 asthmatic children recruited at the Children's Hospital of Mexico and 50 non-asthmatic children were followed for 22 weeks. Pulmonary function was measured and nasal lavage collected and analyzed every 2 weeks. Dietary intake was evaluated using a 108-item food frequency questionnaire and a fruit and vegetable index (FVI) and a Mediterranean diet index (MDI) were constructed. The impact of these indices on lung function and interleukin-8 (IL-8) and their interaction with air pollutants were determined using mixed regression models with random intercept and random slope.
resultsFVI was inversely related to IL-8 levels in nasal lavage (p < 0.02) with a significant inverse trend (test for trend p < 0.001), MDI was positively related to lung function (p < 0.05), and children in the highest category of MDI had a higher FEV1 (test for trend p < 0.12) and FVC (test for trend p < 0.06) than children in the lowest category. A significant interaction was observed between FVI and ozone for FEV1 and FVC as was with MDI and ozone for FVC. No effect of diet was observed among healthy children.
conclusionOur results suggest that fruit and vegetable intake and close adherence to the Mediterranean diet have a beneficial effect on inflammatory response and lung function in asthmatic children living in Mexico City.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.