Evidence map›Paper›PMID 20002077›Full record

ReviewBritish journal of clinical pharmacology2009

Obesity treatment: novel peripheral targets.

Benjamin C T Field, Owais B Chaudhri, Stephen R Bloom

Open access · bronzeAbstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Obesity vaccines.Human vaccines & immunotherapeutics · 2014
    Review
  11. Article
  12. Review
  13. Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  14. Unraveling oxyntomodulin, GLP1's enigmatic brother.The Journal of endocrinology · 2012
    Review
  15. Anti-obesity drugs: past, present and future.Disease models & mechanisms · 2012
    Review
  16. Review
  17. Article
  18. Article
  19. Antipsychotic drugs and obesity.Trends in molecular medicine · 2011
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benjamin C T FieldDepartment of Investigative Medicine, Imperial College London, Hammersmith Hospital Campus, London, UK.
Owais B Chaudhri
Stephen R Bloom
Imperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our knowledge of the complex mechanisms underlying energy homeostasis has expanded enormously in recent years. Food intake and body weight are tightly regulated by the hypothalamus, brainstem and reward circuits, on the basis both of cognitive inputs and of diverse humoral and neuronal signals of nutritional status. Several gut hormones, including cholecystokinin, glucagon-like peptide-1, peptide YY, oxyntomodulin, amylin, pancreatic polypeptide and ghrelin, have been shown to play an important role in regulating short-term food intake. These hormones therefore represent potential targets in the development of novel anti-obesity drugs. This review focuses on the role of gut hormones in short- and long-term regulation of food intake, and on the current state of development of gut hormone-based obesity therapies.

Indexed as

AmyloidAnti-Obesity AgentsAppetite DepressantsAppetite RegulationCholecystokininEatingEnergy MetabolismGastrointestinal AgentsGhrelinHumansIslet Amyloid PolypeptideObesityOxyntomodulinPancreatic PolypeptidePeptide YYAmyloidAnti-Obesity AgentsAppetite DepressantsCholecystokininGastrointestinal AgentsGhrelinIslet Amyloid PolypeptideOxyntomodulinPancreatic PolypeptidePeptide YY

Identifiers

PMID20002077
PMCPMC2810794
OpenAlexW2083741293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.