Evidence map›Paper›PMID 20001425›Full record

ReviewExpert opinion on pharmacotherapy2010

Treatment strategies for dystonia.

Leslie J Cloud, H A Jinnah

Abstract readReview
In one paragraph

Review in Expert opinion on pharmacotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 5 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 5 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Zolpidem for the Treatment of Dystonia.Frontiers in neurology · 2019
    Pooled it
  5. Dystonia rating scales: critique and recommendations.Movement disorders : official journal of the Movement Disorder Society · 2013
    Pooled it
  6. Optimal physiotherapy management strategies for cervical dystonia: an international Delphi study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  7. A scoping review about the efficacy of clonazepam for the treatment of benign essential blepharospasm.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Deep brain stimulation in pediatric dystonia: calls for therapeutic realism over nihilism.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Leslie J CloudEmory University, Department of Neurology, 1841 Clifton Road NE, Room 329, Atlanta, GA 30029, USA.
H A Jinnah
Emory University · USWeatherford College · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Dystonia CoalitionU54NS065701 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2009 to 2014
$7.0M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
NEUROBIOLOGY OF DYSTONIAR01NS040470 · NINDS · JOHNS HOPKINS UNIVERSITY · PI JINNAH, HYDER A · 2000 to 2008
$2.5M
NCATS NIH HHS U54 TR001456NCATS NIH HHS UL1 TR000454NCRR NIH HHS UL1 RR025008NINDS NIH HHS R01 NS040470NINDS NIH HHS U54 NS065701
6 · The paper itself

Abstract

importance of the fieldDystonia is a neurological syndrome characterized by involuntary twisting movements and unnatural postures. It has many different manifestations and causes, and many different treatment options are available. These options include physical and occupational therapy, oral medications, intramuscular injection of botulinum toxins, and neurosurgical interventions. AREAS COVERED IN THIS REVIEW: In this review, we first summarize the treatment options available, then we provide suggestions from our own experience for how these can be applied in different types of dystonia. In preparing this review article, an extensive literature search was undertaken using PubMed. Only selected references from 1970 to 2008 are cited. WHAT THE READER WILL GAIN: This review is intended to provide the clinician with a practical guide to the treatment of dystonia. TAKE HOME MESSAGE: Treatment of dystonia begins with proper diagnosis and classification, followed by an appropriate search for underlying etiology, and an assessment of the functional impairment associated with the dystonia. The therapeutic approach, which is usually limited to symptomatic therapy, must then be tailored to the individual needs of the patient.

Indexed as

Botulinum ToxinsBotulinum Toxins, Type ADeep Brain StimulationDiagnosis, DifferentialDopamine AntagonistsDyskinesiasDystoniaDystonic DisordersHumansInjections, IntramuscularBotulinum ToxinsBotulinum Toxins, Type ADopamine Antagonists

Identifiers

PMID20001425
PMCPMC3495548
OpenAlexW2071058632

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.