ReviewAutoimmunity2010
The biology of reactive intermediates in systemic lupus erythematosus.
Review in Autoimmunity, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 51 citations in OpenAlex.
- Review
- Nitric Oxide Signal Transduction and Its Role in Skin Sensitization.Biomolecules & therapeutics · 2023Review
- Red blood cells in type 1 diabetes and multiple sclerosis and technologies to measure their emerging roles.Journal of translational autoimmunity · 2022Review
- Correlation between C-reactive Protein with Malondialdehyde in Systemic Lupus Erythematosus Patients.International journal of rheumatology · 2020Article
- Immune Complexes Impaired Glomerular Endothelial Cell Functions in Lupus Nephritis.International journal of molecular sciences · 2019Article
- Contribution of poly(ADP-ribose)polymerase-1 activation and apoptosis in trichloroethene-mediated autoimmunity.Toxicology and applied pharmacology · 2019Article
- Increased lipid and protein oxidation and lowered anti-oxidant defenses in systemic lupus erythematosus are associated with severity of illness, autoimmunity, increased adhesion molecules, and Th1 and Th17 immune shift.Immunologic research · 2018Article
- Anti-Inflammatory Effect of Quercetin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid.Molecules (Basel, Switzerland) · 2016Article
- Understanding mechanisms of hypertension in systemic lupus erythematosus.Therapeutic advances in cardiovascular disease · 2016Review
- Cellular and molecular etiology of hepatocyte injury in a murine model of environmentally induced liver abnormality.Open veterinary journal · 2016Article
- iNOS null MRL+/+ mice show attenuation of trichloroethene-mediated autoimmunity: contribution of reactive nitrogen species and lipid-derived reactive aldehydes.Free radical biology & medicine · 2015Article
- T cell PKCδ kinase inactivation induces lupus-like autoimmunity in mice.Clinical immunology (Orlando, Fla.) · 2015Article
- Fish oil N-3 fatty acids increase adiponectin and decrease leptin levels in patients with systemic lupus erythematosus.Marine drugs · 2015Article
- Melanocortin peptides: potential targets in systemic lupus erythematosus.Inflammation · 2015Review
- Article
- N-Acetylcysteine protects against trichloroethene-mediated autoimmunity by attenuating oxidative stress.Toxicology and applied pharmacology · 2013Article
- Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.The Journal of rheumatology · 2013Article
- Article
- HSP90 inhibition by 17-DMAG reduces inflammation in J774 macrophages through suppression of Akt and nuclear factor-κB pathways.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2012Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Systemic lupus erythematosus (SLE) is an autoimmune syndrome marked by autoantibody production. Innate immunity is essential to transform humoral autoimmunity into the clinical lupus phenotype. Nitric oxide (NO) is a membrane- permeable signaling molecule involved in a broad array of biologic processes through its ability to modify proteins, lipids, and DNA and alter their function and immunogenicity. The literature regarding mechanisms through which NO regulates inflammation and cell survival is filled with contradictory findings. However, the effects of NO on cellular processes depend on its concentration and its interaction with reactive oxygen. Understanding this interaction will be essential to determine mechanisms through which reactive intermediates induce cellular autoimmunity and contribute to a sustained innate immune response and organ damage in SLE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.