ArticleHernia : the journal of hernias and abdominal wall surgery2010
Do drainage liquid characteristics serve as predictors for seroma formation after incisional hernia repair?
Article in Hernia : the journal of hernias and abdominal wall surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- The use of adjuncts to reduce seroma in open incisional hernia repair: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2018Pooled it
- Diagnostic and Management Challenges in a Non-Infectious Pacemaker Pocket Swelling: A Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2026Article
- Tissue integration and inflammatory reaction in full-thickness abdominal wall repair using an innovative composite mesh.Hernia : the journal of hernias and abdominal wall surgery · 2016Article
- Surgical resection and scarification for chronic seroma post-ventral hernia mesh repair.The American journal of case reports · 2014Article
- Acute inflammatory response in the subcutaneous versus periprosthethic space after incisional hernia repair: an original article.BMC surgery · 2014Article
- Use of vacuum-assisted closure in open incisional hernia repair: a novel approach to prevent seroma formation.Hernia : the journal of hernias and abdominal wall surgery · 2013Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThough the occurrence of postoperative seroma after incisional hernia repair using mesh reinforcement is very common, little is known about the genesis of seroma formation. The aim of this study was to determine the characteristics of drainage liquid as a potential predictor for the development of seroma after incisional hernia mesh repair. Furthermore, the characteristics of drainage liquid were compared to the characteristics of seroma liquid.
methodsThe incidence of postoperative seroma associated with pH value, concentration of lactate, total protein, albumin, propeptide-III-procollagen (P-III-P), hyaluronan, fibronectin and IL-1 receptor antagonist (IL-1-RA) in the drainage liquid were prospectively determined in 38 patients who underwent incisional hernia repair by lightweight polypropylene-polyglactin composite mesh (Vypro-II). The findings were compared to the seroma liquid characteristics of those patients who developed a seroma formation.
resultsIn 11 patients (29%), seroma formation was present after removal of the drainage. We observed significantly elevated mean drainage volume (148 +/- 64 ml vs. 93 +/- 71 ml; P = 0.014) and significantly reduced pH value (7.26 +/- 0.12 vs. 7.41 +/- 0.23; P = 0.016) and IL-1-RA (100 +/- 71 U/ml vs. 145 +/- 108 U/ml; P = 0.016) in the drainage liquid of patients with seroma formation in comparison to patients without seroma formation. In addition, we found significantly altered concentration of lactate (9.8 +/- 2.0 mmol/l vs. 5.5 +/- 1.4 mmol/l; P < 0.001), P-III-P (24 +/- 13 U/ml vs. 89 +/- 79 U/ml; P = 0.045) and fibronectin (0.10 +/- 0.03 g/l vs. 0.24 +/- 0.13 g/l; P = 0.005) in the drainage liquid in comparison to seroma liquid.
conclusionsThe pH value of wound solution proves to be a reliable predictor for the subsequent presence of seroma formation. Furthermore, our findings implicate that seroma formation cannot be seen as persistent drainage liquid.
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