ReviewDer Unfallchirurg2009
[Impact of hypothermia on the severely injured patient].
Review in Der Unfallchirurg, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 32 citations in OpenAlex.
- The impact of mild induced hypothermia on the rate of transfusion and the mortality in severely injured patients: a retrospective multi-centre study.European journal of medical research · 2016Trial
- Excessive bleeding is a normal cleansing process: a qualitative study of postpartum haemorrhage among rural Uganda women.BMC pregnancy and childbirth · 2016Article
- Damage control resuscitation: lessons learned.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2016Review
- [Diagnostics and treatment strategies for multiple trauma patients].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016Review
- Effects of hypothermia combined with neural stem cell transplantation on recovery of neurological function in rats with spinal cord injury.Molecular medicine reports · 2015Article
- Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model.Mediators of inflammation · 2015Article
- Mild hypothermia combined with a scaffold of NgR-silenced neural stem cells/Schwann cells to treat spinal cord injury.Neural regeneration research · 2014Article
- Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging.Neural regeneration research · 2014Article
- Hypothermia improves oral and gastric mucosal microvascular oxygenation during hemorrhagic shock in dogs.Oxidative medicine and cellular longevity · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accidental hypothermia is a common complication in severely injured patients. Risk factors include environmental exposure of the patient at the accident site or in the clinic, infusion of cold fluids, hemorrhagic shock and anesthetics which influence thermoregulation. In contrast to animal studies, human studies and clinical experiences have identified accidental hypothermia of the severely injured patient to be associated with increased complication and mortality rates. As a consequence, hypothermia together with acidosis and coagulopathy, have been coined the lethal triad in severely injured patients. On a cellular level hypothermia reduces cellular activity and metabolism resulting in reduced oxygen consumption, which is therapeutically used in patients following cardiac arrest. However, the activity of important enzymes, such as those of the coagulation pathway, is simultaneously down regulated. Hypothermia-induced coagulopathy, which is refractory to substitution of coagulation factors, is a major complication of hypothermia in traumatized patients. Therefore, hypothermic trauma patients with hemodynamic instability require aggressive rewarming.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.