Evidence map›Paper›PMID 19997603›Full record

ArticlePloS one2009

Adaptive vaccination strategies to mitigate pandemic influenza: Mexico as a case study.

Gerardo Chowell, Cécile Viboud, Xiaohong Wang, Stefano M Bertozzi, Mark A Miller

Abstract readHistorical Article
In one paragraph

Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
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  3. Evaluating targeted COVID-19 vaccination strategies with agent-based modeling.medRxiv : the preprint server for health sciences · 2023
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  8. Perspectives on the role of mobility, behavior, and time scales in the spread of diseases.Proceedings of the National Academy of Sciences of the United States of America · 2016
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Gerardo ChowellMathematical, Computational & Modeling Sciences Center, School of Human Evolution and Social Change, Arizona State University, Tempe, Arizona, United States of America. gchowell@asu.edu
Cécile Viboud
Xiaohong Wang
Stefano M Bertozzi
Mark A Miller

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

backgroundWe explore vaccination strategies against pandemic influenza in Mexico using an age-structured transmission model calibrated against local epidemiological data from the Spring 2009 A(H1N1) pandemic. METHODS AND

findingsIn the context of limited vaccine supplies, we evaluate age-targeted allocation strategies that either prioritize youngest children and persons over 65 years of age, as for seasonal influenza, or adaptively prioritize age groups based on the age patterns of hospitalization and death monitored in real-time during the early stages of the pandemic. Overall the adaptive vaccination strategy outperformed the seasonal influenza vaccination allocation strategy for a wide range of disease and vaccine coverage parameters.

conclusionsThis modeling approach could inform policies for Mexico and other countries with similar demographic features and vaccine resources issues, with regard to the mitigation of the S-OIV pandemic. We also discuss logistical issues associated with the implementation of adaptive vaccination strategies in the context of past and future influenza pandemics.

Indexed as

VaccinationAdaptive ImmunityAge DistributionDisease OutbreaksHistory, 20th CenturyHospitalizationHumansIncidenceInfluenza A Virus, H1N1 SubtypeInfluenza, HumanInfluenza VaccinesMexicoModels, StatisticalSeasonsInfluenza Vaccines

Identifiers

PMID19997603
PMCPMC2781783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.