Evidence map›Paper›PMID 19997578›Full record

ReviewVascular health and risk management2009

Vascular health in children and adolescents: effects of obesity and diabetes.

Kevin R Short, Piers R Blackett, Andrew W Gardner, Kenneth C Copeland

Open access · goldAbstract readReview
In one paragraph

Review in Vascular health and risk management, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kevin R ShortDepartment of Pediatrics, Section of Diabetes and Endocrinology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Piers R Blackett
Andrew W Gardner
Kenneth C Copeland
University of Oklahoma Health Sciences Center · USUniversity of Oklahoma · US

Funding

Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) StudyU01DK061230 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BRAFFETT, BARBARA HALINA, ZEITLER, PHILIP S. · 2001 to 2019
$231.8M
TRAINING COREP20MD000528 · NIMHD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI STEPHENS, LANCER · 2003 to 2016
$17.8M
THE ROLE OF COMPLEX 1 IN MITOCHONDRIAL DYSFUNCTION & FREE RADICAL PROD IN TYPE 1P20RR024215 · NCRR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI XIE, ZHONGLIN · 2007 to 2011
$11.7M
Trt. of Primary Hyperaldosteronism w/ACE Inhibitors &Angiotension Rec. BlockersM01RR014467 · NCRR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI RATHBUN, SUMAN W · 2001 to 2007
$10.4M
Home-based vs. Supervised Exercise for ClaudicantsR01AG024296 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI GARDNER, ANDREW W · 2006 to 2010
$1.4M
NCRR NIH HHS M01 RR014467NCRR NIH HHS M01-RR-14467NCRR NIH HHS P20 RR024215NCRR NIH HHS P20-RR-024215NIA NIH HHS R01 AG024296NIA NIH HHS R01-AG-24296NIDDK NIH HHS U01 DK061230NIDDK NIH HHS U01-DK061230-09NIMHD NIH HHS P20 MD000528NIMHD NIH HHS P20-MD-000528
6 · The paper itself

Abstract

The foundations for cardiovascular disease in adults are laid in childhood and accelerated by the presence of comorbid conditions, such as obesity, diabetes, hypertension, and dyslipidemia. Early detection of vascular dysfunction is an important clinical objective to identify those at risk for subsequent cardiovascular morbidity and events, and to initiate behavioral and medical interventions to reduce risk. Typically, cardiovascular screening is recommended for young adults, especially in people with a family history of cardiovascular conditions. Children and adolescents were once considered to be at low risk, but with the growing health concerns related to sedentary lifestyle, poor diet and obesity, cardiovascular screening may be needed earlier so that interventions to improve cardiovascular health can be initiated. This review describes comorbid conditions that increase cardiovascular risk in youth, namely obesity and diabetes, and describes noninvasive methods to objectively detect vascular disease and quantify vascular function and structure through measurements of endothelial function, arterial compliance, and intima-media thickness. Additionally, current strategies directed toward prevention of vascular disease in these populations, including exercise, dietary interventions and pharmacological therapy are described.

Indexed as

ArteriesAdolescentAge FactorsAntihypertensive AgentsCardiovascular DiseasesCarotid ArteriesChildComplianceDiabetes Mellitus, Type 2Diagnostic Techniques, CardiovascularDietDisease ProgressionEndothelium, VascularExerciseHumansHypoglycemic AgentsAntihypertensive AgentsHypoglycemic AgentsHypolipidemic Agentsarterial complianceendothelial functioninflammationinterventionintimal medial thickness

Identifiers

PMID19997578
PMCPMC2788602
OpenAlexW1972905705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.