Evidence map›Paper›PMID 19997570›Full record

ArticleVascular health and risk management2009

Low use of statins and other coronary secondary prevention therapies in primary and secondary care in India.

Krishna K Sharma, Rajeev Gupta, Aachu Agrawal, Sanjeeb Roy, Atul Kasliwal, Ajeet Bana, Ravindra K Tongia, Prakash C Deedwania

Open access · goldAbstract read
In one paragraph

Article in Vascular health and risk management, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  11. Translating intentions to prescriptions: Mind the gap!Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2014
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  12. Article
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  15. Age and Gender Disparities in Evidence-based Treatment for Coronary Artery Disease in the Community: A Cross-sectional Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2011
    Article
  16. Article
  17. Impact of the CD40-CD40L dyad in Alzheimer's disease.CNS & neurological disorders drug targets · 2010
    Review
  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Krishna K SharmaDepartment of Pharmacy, LBS College of Pharmacy, Jaipur, India.
Rajeev Gupta
Aachu Agrawal
Sanjeeb Roy
Atul Kasliwal
Ajeet Bana
Ravindra K Tongia
Prakash C Deedwania
Fortis Escorts Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the frequency of use of pharmacotherapy with aspirin, beta blocker, statin, and angiotensin-converting enzyme (ACE) inhibitor in patients with stable coronary heart disease (CHD) among physicians at different levels of health care in Rajasthan state, India.

methodsPhysicians practicing at tertiary hospitals and clinics at tertiary, secondary and primary levels were contacted. Prescriptions of CHD patients were audited and descriptive statistics reported.

resultsWe evaluated 2,993 prescriptions (tertiary hospital discharge 711, tertiary 688, secondary 1,306, and primary 288). Use of aspirin was in 2,713 (91%) of prescriptions, beta blockers 2,057 (69%), ACE inhibitors or angiotensin receptor blockers (ARBs) 2,471 (82%), and statins 2,059 (69%). Any one of these drugs was prescribed in 2,991 (100%), any two in 2,880 (96%), any three in 1,740 (58%), and all four in 1,062 (35.5%) (P < 0.001). As compared to tertiary hospital, prescriptions at tertiary, secondary, and primary levels were lower: aspirin (96% vs 95%, 91%, 67%), beta blockers (80% vs 62%, 66%, 70%), statins (87% vs 82%, 62%, 21%): two drugs (98% vs 96%, 98%, 85%), three drugs (75% vs 58%, 55%, 28%), or four drugs (54% vs 44%, 28%, 7%) (P < 0.01). Use of ACE inhibitors/ARBs was similar while nitrates (43% vs 23%, 43%, 70%), dihydropyridine calcium channel blockers (12% vs 15%, 30%, 47%), and multivitamins (6% vs 26%, 37%, 47%) use was more in secondary and primary care.

conclusionsThere is suboptimal use of various evidence-based drugs (aspirin, beta blockers, ACE inhibitors, and statins) for secondary prevention of CHD in India.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsPractice Patterns, Physicians'Primary Health CareSecondary PreventionAdrenergic beta-AntagonistsAdultAgedAngiotensin-Converting Enzyme InhibitorsAspirinCoronary DiseaseDrug PrescriptionsDrug Therapy, CombinationDrug UtilizationEvidence-Based MedicineFemaleGuideline AdherenceAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAspirinHydroxymethylglutaryl-CoA Reductase InhibitorsPlatelet Aggregation Inhibitorsangiotensin-converting enzyme inhibitoraspirinbeta blockerscoronary heart diseasestatins

Identifiers

PMID19997570
PMCPMC2788593
OpenAlexW2012510468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.