Evidence map›Paper›PMID 19996447›Full record

ArticleThe American journal of tropical medicine and hygiene2009

Niche partitioning of Borrelia burgdorferi and Borrelia miyamotoi in the same tick vector and mammalian reservoir species.

Alan G Barbour, Jonas Bunikis, Bridgit Travinsky, Anne Gatewood Hoen, Maria A Diuk-Wasser, Durland Fish, Jean I Tsao

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 169 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
169citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

169 citing papers in PubMed, 1 synthesis or guideline pooled it, 318 citations in OpenAlex.

  1. Pooled it
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109 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alan G BarbourDepartment of Microbiology and Molecular Genetics, University of California Irvine, Irvine, California 92697-4028, USA. abarbour@uci.edu
Jonas Bunikis
Bridgit Travinsky
Anne Gatewood Hoen
Maria A Diuk-Wasser
Durland Fish
Jean I Tsao
University of California, Irvine · USLouisiana Department of Wildlife and Fisheries · US

Funding

MOLECULAR BASIS OF BORRELIA PATHOGENESISR37AI024424 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARBOUR, ALAN G. · 2001 to 2010
$3.5M
INTERFACE OF BORRELIA SURFACE PROTEINS AND ANTIBODIESR01AI037248 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI BARBOUR, ALAN G. · 1994 to 2004
$1.5M
MOLECULAR BASIS OF BORRELIA PATHOGENESISR01AI024424 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI BARBOUR, ALAN G. · 1987 to 2000
$339k
NCPDCID CDC HHS U01 CI000171NIAID NIH HHS AI24424NIAID NIH HHS AI37248NIAID NIH HHS R01 AI024424NIAID NIH HHS R01 AI037248NIAID NIH HHS R37 AI024424
6 · The paper itself

Abstract

The Lyme borreliosis agent Borrelia burgdorferi and the relapsing fever group species Borrelia miyamotoi co-occur in the United States. We used species-specific, quantitative polymerase chain reaction to study both species in the blood and skin of Peromyscus leucopus mice and host-seeking Ixodes scapularis nymphs at a Connecticut site. Bacteremias with B. burgdorferi or B. miyamotoi were most prevalent during periods of greatest activity for nymphs or larvae, respectively. Whereas B. burgdorferi was 30-fold more frequent than B. miyamotoi in skin biopsies and mice had higher densities of B. burgdorferi densities in the skin than in the blood, B. miyamotoi densities were higher in blood than skin. In a survey of host-seeking nymphs in 11 northern states, infection prevalences for B. burgdorferi and B. miyamotoi averaged approximately 0.20 and approximately 0.02, respectively. Co-infections of P. leucopus or I. scapularis with both B. burgdorferi and B. miyamotoi were neither more nor less common than random expectations.

Indexed as

AnimalsArachnid VectorsBorreliaBorrelia InfectionsDisease ReservoirsHost-Pathogen InteractionsIxodesPeromyscusSkinSpecies Specificity

Identifiers

PMID19996447
PMCPMC2841027
OpenAlexW2121225700

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.