ArticleThe Plant cell2009
Extensive functional diversification of the Populus glutathione S-transferase supergene family.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.
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Who cites it
107 citing papers in PubMed, 220 citations in OpenAlex.
- Non-triazine photosystem II inhibitors provide effective control of metabolic atrazine-resistant Amaranthus tuberculatus.Pest management science · 2026Article
- Large-scale genomic analysis reveals the origin and evolution of Glutathione S-transferases (GSTs) in plants.BMC genomics · 2026Article
- Effects of High Lithium Concentrations on the Growth, Biomass, Mineral Accumulation, Oxidative Stress, Antioxidant and Gene Expression Response, and DNA Methylation in Sunflower Plants.Plants (Basel, Switzerland) · 2026Article
- Evolutionary shift in catalytic function of OsGLYI-10 from a glyoxalase homolog to a glutathione-s-transferase in rice.Plant molecular biology · 2025Article
- Comparative analysis of NAC genes and their expression patterns under various treatments in Dendrobium huoshanense.BMC plant biology · 2025Article
- Research on the GST gene family in Salix lindleyana reveals Trp162 and Pro202 as key amino acids controlling the release rate of GS-X.BMC plant biology · 2025Article
- Genome-Wide Identification and Drought-Responsive Functional Analysis of theAntioxidants (Basel, Switzerland) · 2025Article
- Genome-wide identification and in silico analysis of GSTs reveals hormone mediated stress response in saffron.Frontiers in plant science · 2025Article
- Genome-wide identification, expression and functional analysis of glutathioneFrontiers in plant science · 2025Article
- Evolution and functional characterization of Populus salt stress-responsive calcineurin B-like protein-interacting protein kinases.Plant cell reports · 2024Article
- Overlooked and misunderstood: can glutathione conjugates be clues to understanding plant glutathione transferases?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Genome-Wide Identification of Glutathione S-Transferase Family fromInternational journal of molecular sciences · 2024Article
- Flowering time regulator qFT13-3 involved in soybean adaptation to high latitudes.Plant biotechnology journal · 2024Article
- Temporal transcriptome and metabolome study revealed molecular mechanisms underlying rose responses to red spider mite infestation and predatory mite antagonism.Frontiers in plant science · 2024Article
- Genome-Wide Analysis of Family I84 Protease Inhibitor Genes in Three Bivalves Reveals Important Information About the Protein Family's Evolution.Marine biotechnology (New York, N.Y.) · 2023Article
- Genome-wide characterization of 2OGD superfamily for mining of susceptibility factors responding to various biotic stresses inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Article
- Genome-wide identification and characterization of glutathione S-transferase gene family in Musa acuminata L. AAA group and gaining an insight to their role in banana fruit development.Journal of applied genetics · 2022Article
- The chromosome-scale genome of Phoebe bournei reveals contrasting fates of terpene synthase (TPS)-a and TPS-b subfamilies.Plant communications · 2022Article
- The Enzymatic Antioxidants Activities Changes in Water Plants Tissues Exposed to Chlorpyrifos Stress.Antioxidants (Basel, Switzerland) · 2022Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identifying how genes and their functions evolve after duplication is central to understanding gene family radiation. In this study, we systematically examined the functional diversification of the glutathione S-transferase (GST) gene family in Populus trichocarpa by integrating phylogeny, expression, substrate specificity, and enzyme kinetic data. GSTs are ubiquitous proteins in plants that play important roles in stress tolerance and detoxification metabolism. Genome annotation identified 81 GST genes in Populus that were divided into eight classes with distinct divergence in their evolutionary rate, gene structure, expression responses to abiotic stressors, and enzymatic properties of encoded proteins. In addition, when all the functional parameters were examined, clear divergence was observed within tandem clusters and between paralogous gene pairs, suggesting that subfunctionalization has taken place among duplicate genes. The two domains of GST proteins appear to have evolved under differential selective pressures. The C-terminal domain seems to have been subject to more relaxed functional constraints or divergent directional selection, which may have allowed rapid changes in substrate specificity, affinity, and activity, while maintaining the primary function of the enzyme. Our findings shed light on mechanisms that facilitate the retention of duplicate genes, which can result in a large gene family with a broad substrate spectrum and a wide range of reactivity toward different substrates.
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