Evidence map›Paper›PMID 19996045›Full record

SynthesisArchives of pediatrics & adolescent medicine2009

Improving health outcomes for youth living with the human immunodeficiency virus: a multisite randomized trial of a motivational intervention targeting multiple risk behaviors.

Sylvie Naar-King, Jeffrey T Parsons, Debra A Murphy, Xinguang Chen, D Robert Harris, Marvin E Belzer

Registry-linked trialAbstract readMeta-AnalysisRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Archives of pediatrics & adolescent medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00103532 (Motivational Enhancement to Promote Health and Reduce Risk in HIV-Infected Youth), which is not on this map. Cited by 51 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00103532 nacompletednot on this map

Motivational Enhancement to Promote Health and Reduce Risk in HIV-Infected Youth

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2005 to 2008Enrolled225ConditionsHIV InfectionArmsHealthy Choices - Motivational Enhancement Intervention, Standard care
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 13 syntheses or guidelines pooled it.

  1. Pooled it
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  4. A Systematic Review and Meta-Analysis of Interventions for Orphans and Vulnerable Children Affected by HIV/AIDS Worldwide.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2020
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  11. Motivational interviewing for improving outcomes in youth living with HIV.The Cochrane database of systematic reviews · 2012
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  12. Guideline
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  14. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sylvie Naar-KingWayne State University, Detroit, Michigan, USA. snaarkin@med.wayne.edu
Jeffrey T Parsons
Debra A Murphy
Xinguang Chen
D Robert Harris
Marvin E Belzer

Funding

Adol. Medicine Trials Network for HIV/AIDS InterventionsU01HD040474 · NICHD · WESTAT, INC. · PI HARRIS, DONALD ROBERT · 2001 to 2016
$114.4M
LEADERSHIP GROUP FOR ADOLESCENT MEDICINE TRIALS NETWORKU01HD040533 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILSON, CRAIG M · 2001 to 2016
$76.4M
NICHD NIH HHS U01 HD040474NICHD NIH HHS U01 HD040533NICHD NIH HHS U01-HD040533
6 · The paper itself

Abstract

objectiveTo determine if Healthy Choices, a motivational interviewing intervention targeting multiple risk behaviors, improved human immunodeficiency virus (HIV) viral load.

designA randomized, 2-group repeated measures design with analysis of data from baseline and 6- and 9-month follow-up collected from 2005 to 2007.

settingFive US adolescent medicine HIV clinics.

participantsA convenience sample with at least 1 of 3 risk behaviors (nonadherence to HIV medications, substance abuse, and unprotected sex) was enrolled. The sample was aged 16 to 24 years and primarily African American. Of the 205 enrolled, 19 did not complete baseline data collections, for a final sample size of 186. Young people living with HIV were randomized to the intervention plus specialty care (n = 94) or specialty care alone (n = 92). The 3- and 6-month follow-up rates, respectively, were 86% and 82% for the intervention group and 81% and 73% for controls. Intervention Healthy Choices was a 4-session individual clinic-based motivational interviewing intervention delivered during a 10-week period. Motivational interviewing is a method of communication designed to elicit and reinforce intrinsic motivation for change. Outcome Measure Plasma viral load.

resultsYouth randomized to Healthy Choices showed a significant decline in viral load at 6 months postintervention compared with youth in the control condition (beta = -0.36, t = -2.15, P = .03), with those prescribed antiretroviral medications showing the lowest viral loads. Differences were no longer significant at 9 months.

conclusionA motivational interviewing intervention targeting multiple risk behaviors resulted in short-term improvements in viral load for youth living with HIV. Trial Registration clinicaltrials.gov Identifier: NCT00103532.

Indexed as

Health BehaviorHealth EducationHIV SeropositivityAdolescentAdolescent BehaviorAnti-HIV AgentsFemaleHumansInterviews as TopicMaleMotivationPatient ComplianceRegression AnalysisRisk-TakingSexual BehaviorSubstance-Related DisordersAnti-HIV Agents

Identifiers

PMID19996045
PMCPMC2843389

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.