Evidence map›Paper›PMID 19995616›Full record

ArticleJournal of biomedical informatics2010

Data visualization speeds review of potential adverse drug events in patients on multiple medications.

Jon D Duke, Xiaochun Li, Shaun J Grannis

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Information visualizations of symptom information for patients and providers: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2019
    Pooled it
  2. Visualization approaches to support healthy aging: A systematic review.Journal of innovation in health informatics · 2016
    Pooled it
  3. Article
  4. Article
  5. Article
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  8. Designing a medication timeline for patients and physicians.Journal of the American Medical Informatics Association : JAMIA · 2019
    Article
  9. Article
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  11. Review
  12. Article
  13. Article
  14. Sim•TwentyFive: an interactive visualization system for data-driven decision support.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2012
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jon D DukeRegenstrief Institute, Indianapolis, IN, USA. jduke@regenstrief.org
Xiaochun Li
Shaun J Grannis

Funding

REGENSTRIEF MEDICAL INFORMATICS RESEARCH FELLOWSHIPST15LM007117 · NLM · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FINNELL, JOHN T · 1997 to 2011
$5.0M
NLM NIH HHS T15 LM007117NLM NIH HHS T15LM07117
6 · The paper itself

Abstract

Patients on multiple medications are at increased risk for adverse drug events. While physicians can reduce this risk by regularly reviewing the side-effect profiles of their patients' medications, this process can be time-consuming. We created a decision support system designed to expedite reviewing potential adverse reactions through information visualization. The system includes a database containing 16,340 unique drug and side-effect pairs, representing 250 common medications. A numeric score is assigned to each pair reflecting the strength of association between drug and effect. Based on these scores, the system generates graphical adverse reaction maps for any user-selected combination of drugs. A study comparing speed and accuracy of retrieving side-effect data using this tool versus UpToDate demonstrated a 60% reduction in time to complete a query (61 s vs. 155 s, p < 0.0001) with no decrease in accuracy. These findings suggest that information visualization can significantly expedite review of potential adverse drug events.

Indexed as

Computer GraphicsDecision Support Systems, ClinicalPolypharmacyAlgorithmsDatabases, FactualDrug-Related Side Effects and Adverse ReactionsHumans

Identifiers

PMID19995616
PMCPMC2838979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.