ArticleActa orthopaedica2009
The association between metal allergy, total hip arthroplasty, and revision.
Article in Acta orthopaedica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.
- Fracture of ceramic bearing surfaces following total hip replacement: a systematic review.BioMed research international · 2013Pooled it
- No difference in patient reported outcome and inflammatory response after coated and uncoated total knee arthroplasty - a randomized controlled study.BMC musculoskeletal disorders · 2023Trial
- Metal release and metal allergy after total hip replacement with resurfacing versus conventional hybrid prosthesis.Acta orthopaedica · 2014Trial
- Influence of Chemical Composition on the Physical-Mechanical Properties of Some Experimental Titanium Alloys for Dental Implants.Dentistry journal · 2026Article
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- Modification of Ti13Nb13Zr Alloy Surface via Plasma Electrolytic Oxidation and Silver Nanoparticles Decorating.Materials (Basel, Switzerland) · 2025Article
- Metal Hypersensitivity in Patients With Failure of Joint Prosthesis Treatment.Journal of immunology research · 2025Article
- Electrochemical Polishing of Ti and TiMaterials (Basel, Switzerland) · 2024Article
- Understanding immune-mediated cobalt/chromium allergy to orthopaedic implants: a meta-synthetic review.Arthroplasty (London, England) · 2024Review
- Serum cobalt and chromium concentration following total hip arthroplasty: a Bayesian network meta-analysis.Scientific reports · 2023Article
- Allergic reaction and metal hypersensitivity after shoulder joint replacement.Musculoskeletal surgery · 2023Article
- Lymphocyte transformation test reveals low prevalence of true metal hypersensitivity among pre-operative total knee arthroplasty patients.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Impact of Preoperative Metal Patch Testing on Surgery Using Metal Implants.Arthroplasty today · 2022Article
- Nickel hypersensitivity and skin patch testing in total hip replacement surgery: a systematic review.EFORT open reviews · 2021Review
- Analysis of Chemisorbed Tribo-Film for Ceramic-on-Ceramic Hip Joint Prostheses by Raman Spectroscopy.Journal of functional biomaterials · 2021Article
- Adverse Reaction to Zirconia in a Modern Total Hip Arthroplasty with Ceramic Head.Arthroplasty today · 2020Article
- Is early migration enough to explain late clinical loosening of hip prostheses?EFORT open reviews · 2020Review
- Increased risk of eczema after joint replacement: A population-based retrospective cohort study.Medicine · 2019Observational
- Review
- Serum Immunoglobulin Levels and Complement Function of Tannery Workers in Bangladesh.Journal of health & pollution · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeIt has been speculated that the prevalence of metal allergy may be higher in patients with implant failure. We compared the prevalence and cause of revisions following total hip arthroplasty (THA) in dermatitis patients suspected to have contact allergy and in patients in general with THA. Furthermore, we compared the prevalence of metal allergy in dermatitis patients with and without THA. MATERIALS AND
methodsThe Danish Hip Arthroplasty Registry (DHAR) contained detailed information on 90,697 operations. The Gentofte patch-test database contained test results for patients suspected of having allergic contact dermatitis (n = 18,794). Cases (n = 356) were defined as patch-tested dermatitis patients who also had primary THA performed. Two age- and sex-matched controls (n = 712) from the patch-test database were sought for each case.
resultsThe prevalence of revision was similar in cases (12%) and in patients from the DHAR (13%). The prevalence of metal allergy was similar in cases and controls. However, the prevalence of metal allergy was lower in cases who were patch-tested after operation (6%) than in those who were patch-tested before operation (16%) (OR = 2.9; 95% CI = 1-8).
interpretationWe found that the risk of surgical revision was not increased in patients with metal allergies and that the risk of metal allergy was not increased in cases who were operated, in comparison to controls. Despite some important study limitations, our observations add to the evidence that the risk of complications in metal allergic patients seems limited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.