ArticleHuman genetics1991
Frequency and distribution of aneuploidy in human female gametes.
Article in Human genetics, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Are zona pellucida laser drilling and polar body biopsy safe for in vitro matured oocytes?Journal of assisted reproduction and genetics · 2010Article
- Meiotic recombination in human oocytes.PLoS genetics · 2009Article
- FISH analysis of six chromosomes in unfertilized human oocytes after polar body removal.Journal of assisted reproduction and genetics · 2000Article
- Chromosome 21 disomy in the spermatozoa of the fathers of children with trisomy 21, in a population with a high prevalence of Down syndrome: increased incidence in cases of paternal origin.American journal of human genetics · 1998Article
- The control of mammalian female meiosis: factors that influence chromosome segregation.Journal of assisted reproduction and genetics · 1998Review
- Chromosome 21 detection in human oocyte fluorescence in situ hybridization: possible effect of maternal age.Journal of assisted reproduction and genetics · 1998Article
- Aneuploidy in human sperm: the use of multicolor FISH to test various theories of nondisjunction.American journal of human genetics · 1996Article
- Detection of aneuploidy in human oocytes and corresponding first polar bodies by fluorescent in situ hybridization.Journal of assisted reproduction and genetics · 1996Article
- Paternal isodisomy for chromosome 7 is compatible with normal growth and development in a patient with congenital chloride diarrhea.American journal of human genetics · 1994Article
- A fluorescent in situ hybridization analysis of X chromosome pairing in early human female meiosis.Human genetics · 1994Article
- Cytogenetic analysis of human oocytes parthenogenetically activated by puromycin.Journal of assisted reproduction and genetics · 1994Article
- A 45,X/46,XX/47,XXX female mosaic detected by cytogenetic analysis of unfertilized IVF oocytes.Journal of assisted reproduction and genetics · 1993Article
- Chromosomal analysis of unfertilized human oocytes prepared by a gradual fixation-air drying method.Human genetics · 1993Article
- Visualization of second polar body chromosomes in fertilized and artificially activated mouse oocytes treated with okadaic acid.Journal of assisted reproduction and genetics · 1992Article
- Gamete cytogenetic study in couples with implantation failure: aneuploidy rate is increased in both couple members.Journal of assisted reproduction and geneticsArticle
- Aging and reproductive potential in women.The Yale journal of biology and medicineReview
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the past 6 years, 14 cytogenetic studies on human oocytes recovered during in vitro fertilization procedures have been published; they report contradictory results. The present survey has pooled the more than 1500 oocyte chromosome complements examined to date, in order to determine generalized trends in chromosomal abnormalities of female gametes. The overall frequency of abnormalities in mature oocytes is 24.0% with a large majority of aneuploidies (22.8%) over structural aberrations (1.2%), which could be explained by the difficulty in the detection of structural abnormalities in oocyte chromosome sets. An analysis of the distribution of non-disjunction among all chromosomes was also performed. In the A, C, D, and especially in the G groups, there is a significant difference between the observed non-disjunction and the frequencies expected from an equal partitioning of non-disjunction among all chromosomes. These data are discussed with reference to the differences obtained from cytogenetic studies on human sperm and from investigations on spontaneous abortion.
Indexed as
Identifiers
1997383What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.