Trial reportPaediatric anaesthesia2010
Hypnotic depth and the incidence of emergence agitation and negative postoperative behavioral changes.
Trial report in Paediatric anaesthesia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07473024 (Long-Term Behavioral Outcomes After pEEG-Guided Anesthesia in Children), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long-Term Behavioral Outcomes After pEEG-Guided Anesthesia in Children: A Follow-Up Study Using the Post-Hospitalization Behavior Questionnaire
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- EEG-guided sevoflurane anesthesia vs. standard care in pediatric emergence delirium: a grade-assessed systematic review and meta-analysis with trial sequential analysis.Journal of anesthesia · 2026Pooled it
- Comparison of the Effect of Pyridostigmine and Sugammadex on Emergence Delirium in Pediatric Patients Undergoing Strabismus Surgery: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Can intraoperative electroencephalogram finally prevent emergence delirium in children?Translational pediatrics · 2026Article
- A Prospective Observational Study of Intraoperative Regional Cerebral Desaturation and Negative Postoperative Behavioural Changes After Non-Cardiac Paediatric Surgery.Acta anaesthesiologica Scandinavica · 2025Observational
- The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study.Biomedicines · 2024Article
- Development of a nomogram to predict negative postoperative behavioral changes based on a prospective cohort.BMC anesthesiology · 2023Observational
- Evaluation of a Video-Based Education Intervention for Parents of Children Undergoing Fontan Surgery: A Cluster Randomized Controlled Trial.CJC pediatric and congenital heart disease · 2023Article
- Depth of anesthesia, temperature, and postoperative delirium in children and adolescents undergoing cardiac surgery.BMC anesthesiology · 2023Article
- Desflurane is risk factor for postoperative delirium in older patients' independent from intraoperative burst suppression duration.Frontiers in aging neuroscience · 2023Article
- EEG-Parameter-Guided Anesthesia for Prevention of Emergence Delirium in Children.Brain sciences · 2022Article
- Recovery Profiles of Sevoflurane and Desflurane with or without M-Entropy Guidance in Obese Patients: A Randomized Controlled Trial.Journal of clinical medicine · 2021Article
- Effectiveness of propofol on incidence and severity of emergence agitation on pediatric patients undergo ENT and ophthalmic surgery: Prospective cohort study design.Annals of medicine and surgery (2012) · 2021Article
- A comprehensive examination of the immediate recovery of children following tonsillectomy and adenoidectomy.International journal of pediatric otorhinolaryngology · 2020Article
- Emergence delirium in children is not related to intraoperative burst suppression - prospective, observational electrography study.BMC anesthesiology · 2019Observational
- A laparoscopic gastrectomy approach decreases the incidence and severity of emergence agitation after sevoflurane anesthesia.Journal of anesthesia · 2015Article
- [Negative behavioral changes in children and adolescents after anesthesia : Development of a German language version of the Post Hospitalization Behavior Questionnaire].Der Anaesthesist · 2015Article
- Impact of bispectral index monitoring on postoperative delirium in patients undergoing aortic surgery.HSR proceedings in intensive care & cardiovascular anesthesia · 2011Article
- Pediatric emergence delirium is linked to increased early postoperative negative behavior within two weeks after adenoidectomy: an observational study.Brazilian journal of anesthesiology (Elsevier)Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundEmergence agitation (EA) and negative postoperative behavioral changes (NPOBC) are common in children, although the etiology remains unclear. We investigated whether longer times under deep hypnosis as measured by Bispectral Index (BIS) monitoring would positively correlate with a greater incidence of EA in the PACU and a greater occurrence of NPOBC in children after discharge.
methodsWe enrolled 400 children, 1-12 years old, scheduled for dental procedures under general anesthesia. All children were induced with high concentration sevoflurane, and BIS monitoring was continuous from induction through recovery in the PACU. A BIS reading <45 was considered deep hypnosis. The presence of EA was assessed in the PACU using the Pediatric Anesthesia Emergence Delirium scale. NPOBC were assessed using the Post-Hospital Behavior Questionnaire, completed by parents 3-5 days postoperatively. Data were analyzed using logistic regression, with a P < 0.05 considered statistically significant.
resultsThe incidence of EA was 27% (99/369), and the incidence of NPOBC was 8.8% (28/318). No significant differences in the incidence of EA or NPOBC were seen with respect to length of time under deep hypnosis as measured by a BIS value of <45.
conclusionOur data revealed no significant correlation between the length of time under deep hypnosis (BIS < 45) and the incidence of EA or NPOBC. Within this population, these behavioral disturbances do not appear to be related to the length of time under a deep hypnotic state as measured by the BIS.
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