Evidence map›Paper›PMID 19967531›Full record

ReviewNeuroradiology2010

Acute stroke magnetic resonance imaging: current status and future perspective.

Stephan P Kloska, Max Wintermark, Tobias Engelhorn, Jochen B Fiebach

Open access · greenAbstract readReview
In one paragraph

Review in Neuroradiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. [A diffusion-weighted image denoising algorithm using HOSVD combined with Rician noise corrected model].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  5. Article
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  8. Review
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  10. Review
  11. Article
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  13. Water diffusion reveals networks that modulate multiregional morphological plasticity after repetitive brain stimulation.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  14. Review
  15. Article
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  17. Review
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Stephan P KloskaDepartment of Neuroradiology, University of Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany. stephan.kloska@uk-erlangen.de
Max Wintermark
Tobias Engelhorn
Jochen B Fiebach
Charité - Universitätsmedizin Berlin · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Münster · DEUniversity of Virginia · US

Funding

CTSA: K12 COMPONENTKL2RR024130 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$19.3M
Advanced NeuroImaging for Acute Stroke TreatmentR13NS061371 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WINTERMARK, MAX · 2007 to 2007
$21k
NCRR NIH HHS KL2 RR024130NINDS NIH HHS R13 NS061371
6 · The paper itself

Abstract

Cerebral stroke is one of the most frequent causes of permanent disability or death in the western world and a major burden in healthcare system. The major portion is caused by acute ischemia due to cerebral artery occlusion by a clot. The minority of strokes is related to intracerebral hemorrhage or other sources. To limit the permanent disability in ischemic stroke patients resulting from irreversible infarction of ischemic brain tissue, major efforts were made in the last decade. To extend the time window for thrombolysis, which is the only approved therapy, several imaging parameters in computed tomography and magnetic resonance imaging (MRI) have been investigated. However, the current guidelines neglect the fact that the portion of potentially salvageable ischemic tissue (penumbra) is not dependent on the time window but the individual collateral blood flow. Within the last years, the differentiation of infarct core and penumbra with MRI using diffusion-weighted images (DWI) and perfusion imaging (PI) with parameter maps was established. Current trials transform these technical advances to a redefined patient selection based on physiological parameters determined by MRI. This review article presents the current status of MRI for acute stroke imaging. A special focus is the ischemic stroke. In dependence on the pathophysiology of cerebral ischemia, the basic principle and diagnostic value of different MRI sequences are illustrated. MRI techniques for imaging of the main differential diagnoses of ischemic stroke are mentioned. Moreover, perspectives of MRI for imaging-based acute stroke treatment as well as monitoring of restorative stroke therapy from recent trials are discussed.

Indexed as

Acute DiseaseBrainCerebral AngiographyHumansMagnetic Resonance ImagingModels, NeurologicalStroke

Identifiers

PMID19967531
PMCPMC8177054
OpenAlexW2135398540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.