ReviewJournal of cancer research and clinical oncology2010
Nonfunctional parathyroid carcinoma.
Review in Journal of cancer research and clinical oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Current concepts in parathyroid carcinoma: a single Centre experience.BMC endocrine disorders · 2019Trial
- Diagnosing the silent: the molecular landscape of non-functional parathyroid carcinoma.Virchows Archiv : an international journal of pathology · 2025Review
- Incidental synchronous intrathyroidal parathyroid carcinomas and papillary thyroid microcarcinoma with compressive neck mass and primary hyperparathyroidism: case report and literature review.BMC endocrine disorders · 2024Review
- Imaging Recommendations for Diagnosis and Management of Primary Parathyroid Pathologies: A Comprehensive Review.Cancers · 2024Review
- Case presentation of the smallest non-functional parathyroid carcinoma and review of the literature.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Review
- Parathyroid Retrospective Analysis of Neoplasms Incidence (pTRANI Study): An Italian Multicenter Study on Parathyroid Carcinoma and Atypical Parathyroid Tumour.Journal of clinical medicine · 2023Article
- Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania.Clinical case reports · 2023Article
- A parathyroid cancer with soporous state, depression, and severe cognitive decline in acute renal failure.Clinical case reports · 2023Article
- Association of Parathyroid and Differentiated Thyroid Carcinomas: A Narrative Up-To-Date Review of the Literature.Medicina (Kaunas, Lithuania) · 2022Review
- Management and Outcome of Parathyroid Carcinoma-Induced Primary Hyperparathyroidism: A Single-Centre Experience.International journal of endocrinology · 2021Article
- Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case.The Pan African medical journal · 2017Article
- Endocrine neoplasms in familial syndromes of hyperparathyroidism.Endocrine-related cancer · 2016Review
- Is local resection sufficient for parathyroid carcinoma?Clinics (Sao Paulo, Brazil) · 2015Article
- Non-functional parathyroid carcinoma: a case report and review of the literature.Cancer biology & therapy · 2015Review
- Highly aggressive pathology of non-functional parathyroid carcinoma.Orphanet journal of rare diseases · 2013Article
- Parathyroid carcinoma: update and guidelines for management.Current treatment options in oncology · 2012Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeNonfunctional parathyroid carcinoma (PTC) is one of the rarest malignant diseases and only nine cases have been reported during the last 23 years. We present a case of nonfunctioning PTC and review the literature in an effort to provide a better understanding of this rare disorder.
methodsOne patient with nonfunctioning PTC was presented, detailing the clinical features, histologic findings, diagnosis, and treatment. Together with data from the other nine cases reported last 23 years, the related literature is also reviewed.
resultsThe presented case was a 47-year-old man with a 2-month history of an enlarging painless cervical mass followed by a 2-week history of hoarseness. Clinical and laboratory evaluations failed to reveal evidence of hyperparathyroidism. Pathological analysis of the resected tumor disclosed findings consistent with PTC. The nonsecretory state of the tumor was further supported by immunoreactivity for parathyroid hormone in tissue, and normal serum levels of this peptide and calcium preoperatively and postoperatively.
conclusionMost nonfunctional PTC is detected late due to a paucity of symptoms, of which a palpable neck mass is the most common. Patients with nonfunctioning PTC appear to have a poorer prognosis than do those with functioning parathyroid cancers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.