Evidence map›Paper›PMID 19966911›Full record

ArticleClinical interventions in aging2009

The inclusion of cognition in vascular risk factor clinical practice guidelines.

Kenneth Rockwood, Laura E Middleton, Paige K Moorhouse, Ingmar Skoog, Sandra E Black

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The cognitive impact of atrial fibrillation.The primary care companion for CNS disorders · 2013
    Article
  2. Article
  3. Cardiovascular prevention of cognitive decline.Cardiology research and practice · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kenneth RockwoodDepartment of Medicine, Dalhousie University, Halifax, NS, Canada. kenneth.rockwood@dal.ca
Laura E Middleton
Paige K Moorhouse
Ingmar Skoog
Sandra E Black

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundPeople with vascular risk factors are at increased risk for cognitive impairment as well as vascular disease. The objective of this study was to evaluate whether vascular risk factor clinical practice guidelines consider cognition as an outcome or in connection with treatment compliance.

methodsArticles from PubMed, EMBASE, and the Cochrane Library were assessed by at least two reviewers and were included if: (1) Either hypertension, high cholesterol, diabetes, or atrial fibrillation was targeted; (2) The guideline was directed at physicians; (3) Adult patients (aged 19 years or older) were targeted; and (4) The guideline was published in English. Of 91 guidelines, most were excluded because they were duplicates, older versions, or focused on single outcomes.

resultsOf the 20 clinical practice guidelines that met inclusion criteria, five mentioned cognition. Of these five, four described potential treatment benefits but only two mentioned that cognition may affect compliance. No guidelines adequately described how to screen for cognitive impairment.

conclusionDespite evidence that links cognitive impairment to vascular risk factors, only a minority of clinical practice guidelines for the treatment of vascular risk factors consider cognition as either an adverse outcome or as a factor to consider in treatment.

Indexed as

CognitionOutcome Assessment, Health CarePractice Guidelines as TopicAdultAgedCerebrovascular DisordersDementiaEvidence-Based MedicineHumansMiddle AgedPatient ComplianceReview Literature as TopicRisk FactorsVascular DiseasesYoung Adultclinical practice guidelinescognitionevidence-based medicinetarget organ damagevascular risk

Identifiers

PMID19966911
PMCPMC2785866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.