ArticleThe Plant cell2009
A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 159 citations in OpenAlex.
- Review
- GWAS and Candidate Gene Prediction of Elemental Accumulation Traits in Rice Using a Multiparental Population.Rice (New York, N.Y.) · 2026Article
- Article
- Molecular bases of circadian magnesium rhythms across eukaryotes.FEBS letters · 2026Article
- Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Multiple omics analysis reveals the response mechanism of tobacco seedlings to different magnesium concentrations.BMC plant biology · 2026Article
- Genome-wide identification, evolutionary dynamics, and abiotic stress response networks of the magnesium transporter gene family in foxtail millet (Frontiers in plant science · 2026Article
- Comparative genomics revealed the gene evolution and functional divergence ofFrontiers in plant science · 2026Article
- Magnesium: An overlooked signalling ion in plant physiology and circadian regulation.Quantitative plant biology · 2026Review
- Identification of MRS2 Gene Family and Expression Analysis in Response to Magnesium Treatment inPlants (Basel, Switzerland) · 2025Article
- Metabolome profiling and transcriptome analysis unveiling the crucial role of magnesium transport system for magnesium homeostasis in tea plants.Horticulture research · 2024Article
- Unraveling the genetics of heat tolerance in chickpea landraces (Frontiers in plant science · 2024Article
- Integrative transcriptomic analysis reveals the molecular responses of tobacco to magnesium deficiency.Frontiers in plant science · 2024Article
- Article
- Identification and Expression of the CorA/MRS2/ALR Type Magnesium Transporters in Tomato.Plants (Basel, Switzerland) · 2023Article
- Mutations in RZF1, a zinc-finger protein, reduce magnesium uptake in roots and translocation to shoots in rice.Plant physiology · 2023Article
- Mapping QTLs and gene validation studies for MgFrontiers in plant science · 2023Article
- Genome-wide identification of MgFrontiers in plant science · 2023Article
- Two transporters mobilize magnesium from vacuolar stores to enable plant acclimation to magnesium deficiency.Plant physiology · 2022Article
- Structural and functional comparison of magnesium transporters throughout evolution.Cellular and molecular life sciences : CMLS · 2022Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The MRS2/MGT gene family in Arabidopsis thaliana belongs to the superfamily of CorA-MRS2-ALR-type membrane proteins. Proteins of this type are characterized by a GMN tripeptide motif (Gly-Met-Asn) at the end of the first of two C-terminal transmembrane domains and have been characterized as magnesium transporters. Using the recently established mag-fura-2 system allowing direct measurement of Mg(2+) uptake into mitochondria of Saccharomyces cerevisiae, we find that all members of the Arabidopsis family complement the corresponding yeast mrs2 mutant. Highly different patterns of tissue-specific expression were observed for the MRS2/MGT family members in planta. Six of them are expressed in root tissues, indicating a possible involvement in plant magnesium supply and distribution after uptake from the soil substrate. Homozygous T-DNA insertion knockout lines were obtained for four members of the MRS2/MGT gene family. A strong, magnesium-dependent phenotype of growth retardation was found for mrs2-7 when Mg(2+) concentrations were lowered to 50 microM in hydroponic cultures. Ectopic overexpression of MRS2-7 from the cauliflower mosaic virus 35S promoter results in complementation and increased biomass accumulation. Green fluorescent protein reporter gene fusions indicate a location of MRS2-7 in the endomembrane system. Hence, contrary to what is frequently found in analyses of plant gene families, a single gene family member knockout results in a strong, environmentally dependent phenotype.
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