ArticleGenetics2010
A comprehensive linkage map of the dog genome.
Article in Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed.
- Balanced polymorphism underlies long-standing adaptation for seasonal camouflage in the least weasel.Communications biology · 2026Article
- Genomic information increases prediction accuracy of behavior traits of Labrador Retrievers used as guide dogs.Genetics, selection, evolution : GSE · 2026Article
- Fine-scale recombination rates inferred using the canFam4 assembly are strongly correlated with previous maps of dog recombination.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Article
- A Novel Conservation Genomic Strategy: Selection for the Probability of Offspring Heterozygosity.Animals : an open access journal from MDPI · 2025Article
- Identification of novel genetic mutations for the treatment prognostication of canine lymphoma.NPJ precision oncology · 2025Article
- Article
- Ancient dog introgression into the Iberian wolf genome may have facilitated adaptation to human-dominated landscapes.Genome research · 2025Article
- Canine RNF170 Single Base Deletion in a Naturally Occurring Model for Human Neuroaxonal Dystrophy.Movement disorders : official journal of the Movement Disorder Society · 2024Article
- Comparative Population Genomics of Arctic Sled Dogs Reveals a Deep and Complex History.Genome biology and evolution · 2024Article
- Low but highly geographically structured genomic diversity of East Asian Eurasian otters and its conservation implications.Evolutionary applications · 2024Article
- Homozygosity mapping in the Kazakh national dog breed Tazy.Scientific reports · 2023Article
- Reviving ghost alleles: Genetically admixed coyotes along the American Gulf Coast are critical for saving the endangered red wolf.Science advances · 2022Article
- Construction of a chromosome-level Japanese stickleback species genome using ultra-dense linkage analysis with single-cell sperm sequencing.NAR genomics and bioinformatics · 2022Article
- Improving the resolution of canine genome-wide association studies using genotype imputation: A study of two breeds.Animal genetics · 2021Article
- Genomic architecture constrained placental mammal X Chromosome evolution.Genome research · 2021Article
- Article
- A novel canine reference genome resolves genomic architecture and uncovers transcript complexity.Communications biology · 2021Article
- The Effects of Quantitative Trait Architecture on Detection Power in Short-Term Artificial Selection Experiments.G3 (Bethesda, Md.) · 2020Article
- Genomic evidence for the Old divergence of Southern European wolf populations.Proceedings. Biological sciences · 2020Article
- Sex Differences in the Recombination Landscape.The American naturalist · 2020Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
We have leveraged the reference sequence of a boxer to construct the first complete linkage map for the domestic dog. The new map improves access to the dog's unique biology, from human disease counterparts to fascinating evolutionary adaptations. The map was constructed with approximately 3000 microsatellite markers developed from the reference sequence. Familial resources afforded 450 mostly phase-known meioses for map assembly. The genotype data supported a framework map with approximately 1500 loci. An additional approximately 1500 markers served as map validators, contributing modestly to estimates of recombination rate but supporting the framework content. Data from approximately 22,000 SNPs informing on a subset of meioses supported map integrity. The sex-averaged map extended 21 M and revealed marked region- and sex-specific differences in recombination rate. The map will enable empiric coverage estimates and multipoint linkage analysis. Knowledge of the variation in recombination rate will also inform on genomewide patterns of linkage disequilibrium (LD), and thus benefit association, selective sweep, and phylogenetic mapping approaches. The computational and wet-bench strategies can be applied to the reference genome of any nonmodel organism to assemble a de novo linkage map.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.