ArticleJournal of bacteriology2010
Noncoding RNA of glutamine synthetase I modulates antibiotic production in Streptomyces coelicolor A3(2).
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- Interplay between Non-Coding RNA Transcription, Stringent/Relaxed Phenotype and Antibiotic Production inAntibiotics (Basel, Switzerland) · 2021Article
- Synthetic biology approaches to actinomycete strain improvement.FEMS microbiology letters · 2021Review
- sRNA scr5239 Involved in Feedback Loop Regulation ofFrontiers in microbiology · 2019Article
- RNase III-Binding-mRNAs Revealed Novel Complementary Transcripts inFrontiers in microbiology · 2017Article
- Engineering microbial hosts for production of bacterial natural products.Natural product reports · 2016Review
- Identification of metE as a second target of the sRNA scr5239 in Streptomyces coelicolor.PloS one · 2015Article
- Article
- Small non-coding RNAs in streptomycetes.RNA biology · 2014Review
- SdrA, a new DeoR family regulator involved in Streptomyces avermitilis morphological development and antibiotic production.Applied and environmental microbiology · 2013Article
- Comparative analysis of non-coding RNAs in the antibiotic-producing Streptomyces bacteria.BMC genomics · 2013Article
- Molecular regulation of antibiotic biosynthesis in streptomyces.Microbiology and molecular biology reviews : MMBR · 2013Review
- Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2).PloS one · 2013Article
- Prediction and characterization of small non-coding RNAs related to secondary metabolites in Saccharopolyspora erythraea.PloS one · 2013Article
- RIsearch: fast RNA-RNA interaction search using a simplified nearest-neighbor energy model.Bioinformatics (Oxford, England) · 2012Article
- Comparative Proteomic Analysis of saccharopolyspora spinosa SP06081 and PR2 strains reveals the differentially expressed proteins correlated with the increase of spinosad yield.Proteome science · 2011Article
- cis-antisense RNA, another level of gene regulation in bacteria.Microbiology and molecular biology reviews : MMBR · 2011Review
- A simple and efficient method to search for selected primary transcripts: non-coding and antisense RNAs in the human pathogen Enterococcus faecalis.Nucleic acids research · 2011Article
- Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2).BMC research notes · 2011Article
- Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2).Microbial biotechnology · 2011Article
- nocoRNAc: characterization of non-coding RNAs in prokaryotes.BMC bioinformatics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Overexpression of antisense chromosomal cis-encoded noncoding RNAss (ncRNAs) in glutamine synthetase I resulted in a decrease in growth, protein synthesis, and antibiotic production in Streptomyces coelicolor. In addition, we predicted 3,597 cis-encoded ncRNAs and validated 13 of them experimentally, including several ncRNAs that are differentially expressed in bacterial hormone-defective mutants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.