ArticleClinical journal of the American Society of Nephrology : CJASN2010
Outcomes associated with in-center nocturnal hemodialysis from a large multicenter program.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02887391 (Comparing Nutritional Status of In-centre Nocturnal Hemodialysis Patients to Conventional Hemodialysis Patients), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparing Nutritional Status of In-centre Nocturnal Hemodialysis Patients to Conventional Hemodialysis Patients: A Prospective Cohort Study
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of Nocturnal Hemodialysis versus Conventional Hemodialysis on End-Stage Renal Disease: A Meta-Analysis and Systematic Review.PloS one · 2017Pooled it
- Nutritional Status in Nocturnal Hemodialysis Patients - A Systematic Review with Meta-Analysis.PloS one · 2016Pooled it
- Effect of lowering dialysate sodium concentration on interdialytic weight gain and blood pressure in patients undergoing thrice-weekly in-center nocturnal hemodialysis: a quality improvement study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2011Trial
- An Observational Study of the First 100 Patients Undergoing Nocturnal Every-Other-Day Online Hemodiafiltration: Clinical Outcomes and Patient and Technique Survival.Journal of clinical medicine · 2025Article
- The role of intra- and interdialytic sodium balance and restriction in dialysis therapies.Frontiers in medicine · 2023Review
- Review
- In-center Nocturnal Hemodialysis Reduced the Circulating FGF23, Left Ventricular Hypertrophy, and All-Cause Mortality: A Retrospective Cohort Study.Frontiers in medicine · 2022Article
- Survival of patients treated with extended-hours haemodialysis in Europe: an analysis of the ERA-EDTA Registry.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
- Observational
- Extended Duration Nocturnal Hemodialysis and Changes in Plasma Metabolite Profiles.Clinical journal of the American Society of Nephrology : CJASN · 2018Observational
- Mortality and Hospitalizations in Intensive Dialysis: A Systematic Review and Meta-Analysis.Canadian journal of kidney health and disease · 2018Article
- Extended-hours hemodialysis is associated with lower mortality risk in patients with end-stage renal disease.Kidney international · 2016Article
- Article
- A 4-month programme of in-centre nocturnal haemodialysis was associated with improvements in patient outcomes.Clinical kidney journal · 2015Article
- Predictors of treatment with dialysis modalities in observational studies for comparative effectiveness research.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2015Observational
- Is peritoneal dialysis still an equal option? Results of the Berlin pediatric nocturnal dialysis program.Pediatric nephrology (Berlin, Germany) · 2015Article
- Hemodiafiltration in a pediatric nocturnal dialysis program.Pediatric nephrology (Berlin, Germany) · 2014Article
- Cost analysis of in-centre nocturnal compared with conventional hemodialysis.Canadian journal of kidney health and disease · 2014Article
- Nocturnal hemodialysis.Indian journal of nephrology · 2012Article
- Selectively increasing the clearance of protein-bound uremic solutes.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2012Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesThe objective of this study was to evaluate epidemiology and outcomes of a large in-center nocturnal hemodialysis (INHD) program. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This case-control study compared patients who were on thrice-weekly INHD from 56 Fresenius Medical Care, North America facilities with conventional hemodialysis patients from 244 facilities within the surrounding geographic area. All INHD cases and conventional hemodialysis control subjects who were active as of January 1, 2007, were followed until December 31, 2007, for evaluation of mortality and hospitalization.
resultsAs of January 1, 2007, 655 patients had been on INHD for 51 +/- 73 d. Patients were younger, there were more male and black patients, and vintage was longer, but they had less diabetes compared with 15,334 control subjects. Unadjusted hazard ratio was 0.59 for mortality and 0.76 for hospitalization. After adjustment for case mix and access type, only hospitalization remained significant. Fewer INHD patients were hospitalized (48 versus 59%) with a normalized rate of 9.6 versus 13.5 hospital days per patient-year. INHD patients had greater interdialytic weight gains but lower BP. At baseline, hemoglobin values were similar, whereas albumin and phosphorus values favored INHD. Mean equilibrated Kt/V was higher in INHD patients related to longer treatment time, despite lower blood and dialysate flow rates.
conclusionsPatients who were on INHD exhibited excellent quality indicators, with better survival and lower hospitalization rates. The relative contributions of patient selection versus effect of therapy on outcomes remain to be elucidated in prospective clinical trials.
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