ReviewCurrent opinion in cell biology2010
Intraflagellar transport: it's not just for cilia anymore.
Review in Current opinion in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 113 citations in OpenAlex.
- IFT20 regulates TFEB-dependent lytic granule biogenesis in cytotoxic T lymphocytes by orchestrating the MPR-dependent transport of granzyme B.Cell death & disease · 2025Article
- Delivery of intraflagellar transport proteins to the ciliary base and assembly into trains.Science advances · 2025Article
- De-Suppression of Mesenchymal Cell Identities and Variable Phenotypic Outcomes Associated with Knockout ofCells · 2023Article
- Physical aspects of electro osmotically interactive Cilia propulsion on symmetric plus asymmetric conduit flow of couple stress fluid with thermal radiation and heat transfer.Scientific reports · 2023Article
- Hyperoxia impairs intraflagellar transport and causes dysregulated metabolism with resultant decreased cilia length.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- A Novel Algicidal Bacterium,Microbiology spectrum · 2022Article
- The Bardet-Biedl syndrome complex component BBS1 controls T cell polarity during immune synapse assembly.Journal of cell science · 2021Article
- Cellular and developmental basis of orofacial clefts.Birth defects research · 2020Review
- Physiological and Pathophysiological Aspects of Primary Cilia-A Literature Review with View on Functional and Structural Relationships in Cartilage.International journal of molecular sciences · 2020Review
- Touching the Surface: Diverse Roles for the Flagellar Membrane in Kinetoplastid Parasites.Microbiology and molecular biology reviews : MMBR · 2020Review
- TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating.Nature communications · 2020Article
- Expression of IFT140 During Bone Development.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2019Article
- Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse.Nature communications · 2019Article
- Three-dimensional architecture of epithelial primary cilia.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.PLoS genetics · 2019Article
- Dissecting the Vesicular Trafficking Function of IFT Subunits.Frontiers in cell and developmental biology · 2019Review
- Intraflagellar transport proteins are involved in thrombocyte filopodia formation and secretion.Platelets · 2018Article
- Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.Experimental & molecular medicine · 2018Article
- DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.Scientific reports · 2017Article
- Functional Diversity of Ciliary Proteins in Bone Development and Disease.Current osteoporosis reports · 2017Review
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Recently published information on the role of intraflagellar transport (IFT) polypeptides in vesicle exocytosis is reviewed, describing the formation of the immune synapse in nonciliated cells as an example. A hypothesis is detailed suggesting that all polypeptides which enter the cilium, both membrane and axonemal, do so in association, first, with cytoplasmic vesicles which exocytose adjacent to the ciliary basal body, and then with the ciliary membrane. Axonemal proteins are moved to the ciliary tip by peripheral association with the inner aspects of the ciliary membrane by cannonical ciliary IFT. At the tip, some polypeptides are released for axonemal assembly, and others are budded off as part of vesicular exosomes into the environment. It is proposed that the cilium, in addition to being a sensory and motile organelle, is also a secretory organelle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.