ArticleBrain, behavior, and immunity2010
Socioeconomic status associated with exhaled nitric oxide responses to acute stress in children with asthma.
Article in Brain, behavior, and immunity, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Psychosocial factors and behavioral medicine interventions in asthma.Journal of consulting and clinical psychology · 2013Pooled it
- Situating household management of children's asthma in the context of social, economic, and environmental injustice.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022Article
- Boosting nitric oxide in stress and respiratory infection: Potential relevance for asthma and COVID-19.Brain, behavior, & immunity - health · 2021Review
- Not Breathing Easy: "Disarticulated Homework" in Asthma Management.Medical anthropology quarterly · 2021Article
- Temporal patterns of suicide and circulatory system disease-related mortality are inversely correlated in several countries.BMC psychiatry · 2021Article
- Chronic stress and asthma in adolescents.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020Review
- Article
- Divergent transcriptional profiles in pediatric asthma patients of low and high socioeconomic status.Pediatric pulmonology · 2018Article
- Associations between self-rated health, sickness behaviour and inflammatory markers in primary care patients with allergic asthma: a longitudinal study.NPJ primary care respiratory medicine · 2017Article
- Prevalence of high fractional exhaled nitric oxide among US youth with asthma.Pediatric pulmonology · 2017Article
- Mind-body interactions in the regulation of airway inflammation in asthma: A PET study of acute and chronic stress.Brain, behavior, and immunity · 2016Article
- Shift-and-Persist Strategies: Associations With Socioeconomic Status and the Regulation of Inflammation Among Adolescents and Their Parents.Psychosomatic medicine · 2015Article
- Social disadvantage and asthma control in children.Paediatric respiratory reviews · 2014Review
- Prospectively assessed early life experiences in relation to cortisol reactivity in adolescents at risk for asthma.Developmental psychobiology · 2013Article
- Clinical potentials for measuring stress in youth with asthma.Immunology and allergy clinics of North America · 2011Review
- Low-Grade Inflammation and Ambulatory Cortisol in Adolescents: Interaction Between Interviewer-Rated Versus Self-Rated Acute Stress and Chronic Stress.Psychosomatic medicineArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Although psychosocial stress has been linked to clinical asthma outcomes, controlled, laboratory paradigms that test associations between psychosocial stress and markers of airway inflammation in humans are lacking. There is also little known about how individual background characteristics may affect variability across individuals in asthma-relevant inflammatory and pulmonary responses to stress. The goals of this study were to investigate the effects of a laboratory stress paradigm on markers of airway inflammation and pulmonary function in children with asthma, and to determine why some children are more biologically responsive to stress. 38 children physician-diagnosed with asthma, and 23 healthy control children (M age=15 years) engaged in a conflict discussion task with a parent. Pulmonary function (FEV(1)) was measured before and immediately after the task. Airway inflammation (indicated by exhaled nitric oxide, FeNO) was measured before and 45 min after the task (to minimize effects from spirometry). Parents were interviewed about family socioeconomic status (SES: income and occupation). In children with asthma only, there was an inverse association of SES with change in FeNO levels in response to the conflict task, meaning that as SES declined, greater increases in FeNO were observed No changes in FEV(1) were found in response to the conflict task. This study suggests that lower SES children with asthma may be more vulnerable to heightened airway inflammation in response to stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.