ArticleArchives of pathology & laboratory medicine2009
Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations.
Article in Archives of pathology & laboratory medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Validating whole slide imaging for diagnostic purposes in pathology: guideline from the College of American Pathologists Pathology and Laboratory Quality Center.Archives of pathology & laboratory medicine · 2013Guideline
- Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter Blinded Randomized Noninferiority Study of 1992 Cases (Pivotal Study).The American journal of surgical pathology · 2018Trial
- Defining a 'cells to society' research framework for appendiceal tumours.Nature reviews. Cancer · 2025Review
- Digital Pathology Allows for Global Second Opinions for Urologic Malignancies.Current urology reports · 2025Review
- A neural cell automated analysis system based on pathological specimens in a gerbil brain ischemia model.Acta cirurgica brasileira · 2024Article
- The experience of introducing telepathology in Mongolia.Journal of pathology informatics · 2023Article
- DigiPatICS: Digital Pathology Transformation of the Catalan Health Institute Network of 8 Hospitals-Planification, Implementation, and Preliminary Results.Diagnostics (Basel, Switzerland) · 2022Article
- Integrated digital pathology at scale: A solution for clinical diagnostics and cancer research at a large academic medical center.Journal of the American Medical Informatics Association : JAMIA · 2021Article
- Verification and Validation of Digital Pathology (Whole Slide Imaging) for Primary Histopathological Diagnosis: All Wales Experience.Journal of pathology informatics · 2021Article
- Whole Slide Imaging for Teleconsultation: The Mount Sinai Hospital, Labcorp Dianon, and Philips Collaborative Experience.Journal of pathology informatics · 2021Article
- Validation of a Portable Whole-Slide Imaging System for Frozen Section Diagnosis.Journal of pathology informatics · 2021Article
- Remote Reporting from Home for Primary Diagnosis in Surgical Pathology: A Tertiary Oncology Center Experience during the COVID-19 Pandemic.Journal of pathology informatics · 2021Article
- Validation of a digital pathology system including remote review during the COVID-19 pandemic.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020Article
- Whole Slide Imaging (WSI) in Pathology: Current Perspectives and Future Directions.Journal of digital imaging · 2020Review
- Precise Identification of Cell and Tissue Features Important for Histopathologic Diagnosis by a Whole Slide Imaging System.Journal of pathology informatics · 2020Article
- Super-resolution recurrent convolutional neural networks for learning with multi-resolution whole slide images.Journal of biomedical optics · 2019Article
- Whole slide imaging equivalency and efficiency study: experience at a large academic center.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019Article
- The California Telepathology Service: UCLA's Experience in Deploying a Regional Digital Pathology Subspecialty Consultation Network.Journal of pathology informatics · 2019Article
- Clinical Application of a Real-Time Telepathology System for Frozen Section Diagnosis in Comparison With Optical Microscope.Frontiers in medicine · 2019Article
- Convolutional neural networks for whole slide image superresolution.Biomedical optics express · 2018Article
Corrections and comments
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Authors and funding
25 authors.
Funding
Abstract
context-Whole-slide imaging technology offers promise for rapid, Internet-based telepathology consultations between institutions. Before implementation, technical issues, pathologist adaptability, and morphologic pitfalls must be well characterized.
objective-To determine whether interpretation of whole-slide images differed from glass-slide interpretation in difficult surgical pathology cases.
design-Diagnostically challenging pathology slides from a variety of anatomic sites from an outside laboratory were scanned into whole digital format. Digital and glass slides were independently diagnosed by 2 subspecialty pathologists. Reference, digital, and glass-slide interpretations were compared. Operator comments on technical issues were gathered.
results-Fifty-three case pairs were analyzed. There was agreement among digital, glass, and reference diagnoses in 45 cases (85%) and between digital and glass diagnoses in 48 (91%) cases. There were 5 digital cases (9%) discordant with both reference and glass diagnoses. Further review of each of these cases indicated an incorrect digital whole-slide interpretation. Neoplastic cases showed better correlation (93%) than did cases of nonneoplastic disease (88%). Comments on discordant cases related to digital whole technology focused on issues such as fine resolution and navigating ability at high magnification.
conclusions-Overall concordance between digital whole-slide and standard glass-slide interpretations was good at 91%. Adjustments in technology, case selection, and technology familiarization should improve performance, making digital whole-slide review feasible for broader telepathology subspecialty consultation applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.