ReviewJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2009
The pharmacologic management of insomnia in patients with HIV.
Review in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Non-pharmacological interventions for improving sleep in people living with HIV: a systematic narrative review.Frontiers in neurology · 2023Pooled it
- Sleep deficiency among people living with human immunodeficiency virus: A growing challenge.HIV medicine · 2024Review
- Article
- Trazodone in the Management of Major Depression Among Elderly Patients with Dementia: A Narrative Review and Clinical Insights.Neuropsychiatric disease and treatment · 2023Article
- Metabolomics of sleep disorders in HIV: a narrative review.Sleep & breathing = Schlaf & Atmung · 2020Review
- Insomnia as an Independent Predictor of Incident Cardiovascular Disease in HIV: Data From the Veterans Aging Cohort Study.Journal of acquired immune deficiency syndromes (1999) · 2019Article
- End-of-Life Care and Bereavement Issues in Human Immunodeficiency Virus-AIDS.The Nursing clinics of North America · 2018Review
- Sleep, function and HIV: a multi-method assessment.AIDS and behavior · 2013Article
- Associations of cytokines, sleep patterns, and neurocognitive function in youth with HIV infection.Clinical immunology (Orlando, Fla.) · 2012Article
- Prevalence and factors associated with sleep disturbances among early-treated HIV-infected persons.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012Article
- The association of fatigue with depression and insomnia in HIV-seropositive patients: a pilot study.Sleep · 2011Article
- Safety considerations in drug treatment of depression in HIV-positive patients: an updated review.Drug safety · 2011Review
- Beyond Ockham's razor: redefining problem-solving in clinical sleep medicine using a "five-finger" approach.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2010Review
- Insomnia in older HIV-positive patients.Sleep science (Sao Paulo, Brazil)Review
- Sleep disturbances in persons living with HIV.The Journal of the Association of Nurses in AIDS Care : JANACArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insomnia is common in human immunodeficiency virus (HIV) seropositive populations. Some studies have estimated as many as 70% of HIV patients experience insomnia at some point during their illness. Insomnia has been linked to reduced quality of life as well as treatment non-adherence in these patients. However, there has been very limited research on the treatment of insomnia in this setting. Lacking treatment trials, we carried out a review of the available literature relevant to the pharmacologic treatment of insomnia in HIV seropositive individuals in order to provide guidance for the clinical management of this complex population. A systematic MEDLINE search was performed using as search terms each of the FDA approved or commonly prescribed insomnia medications and "insomnia and HIV." In addition, we reviewed the published literature on HIV therapies and common comorbid conditions and their interactions with insomnia therapies. We found 4 primary factors affecting the pharmacotherapy of insomnia in individuals with HIV: (1) medications used to treat HIV; (2) antibiotics used to treat opportunistic infections; (3) the HIV infection itself; and (4) conditions frequently associated with HIV infection. The means by which these factors affect the expected risk-benefit profile of insomnia therapies is discussed, and recommendations are made for choosing medications in patients encountered in clinical practice.
Indexed as
Identifiers
19960648PMC2699172W2256844496What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.